Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 4/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 11/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 9/20 | 0.50 |
| ▸ | CLK4 | Q9HAZ1 | 8/20 | 0.50 |
| ▸ | USP2 | O75604 | 4/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.45 |
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30519914 | 1.00 | MAP4K4 (0.56) | MAP4K4CYP1A2ALDH1A1CYP3A4CLK4 | |
| SCHEMBL30520034 | 0.87 | MAP4K4 (0.53) | MAP4K4CYP1A2ALDH1A1CYP3A4CLK4 | |
| SCHEMBL30520132 | 0.87 | MAP4K4 (0.53) | MAP4K4CYP1A2ALDH1A1CYP3A4CLK4 | |
| SCHEMBL25369200 | 0.87 | MAP4K4 (0.53) | MAP4K4CYP1A2ALDH1A1CYP3A4CLK4 | |
| SCHEMBL25366781 | 0.87 | MAP4K4 (0.53) | MAP4K4CYP1A2ALDH1A1CYP3A4CLK4 | |
| SCHEMBL25365404 | 0.87 | ALDH1A1 (0.47) | MAP4K4CYP1A2ALDH1A1CYP3A4CLK4 | |
| SCHEMBL30520125 | 0.87 | ALDH1A1 (0.47) | MAP4K4CYP1A2ALDH1A1CYP3A4CLK4 | |
| SCHEMBL25367687 | 0.86 | TGFBR1 (0.47) | MAP4K4CYP1A2ALDH1A1CYP3A4CLK4 | |
| SCHEMBL30520035 | 0.86 | TGFBR1 (0.47) | MAP4K4CYP1A2ALDH1A1CYP3A4CLK4 | |
| SCHEMBL25367694 | 0.85 | ALDH1A1 (0.46) | MAP4K4CYP1A2ALDH1A1CYP3A4CLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250243194-A1 | ANTAGONIST OF ADENOSINE RECEPTORS | JANSSEN PHARMACEUTICA NV (BE) | 2025-07-31 | — | — | US | disclosed |
| EP-4469452-A1 | ANTAGONIST OF ADENOSINE RECEPTORS | Adorx therapeutics Limited (GB) | 2024-12-04 | — | — | EP | disclosed |
| WO-2023144559-A1 | ANTAGONIST OF ADENOSINE RECEPTORS | AdoRx Therapeutics Limited (GB) | 2023-08-03 | — | — | WO | disclosed |
| WO-2023144559-A1 | ANTAGONIST OF ADENOSINE RECEPTORS | AdoRx Therapeutics Limited (GB) | 2023-08-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250243194-A1 | ANTAGONIST OF ADENOSINE RECEPTORS | ADORA2B, ADORA2A, ADORA1 | MAP4K4 3782/4885CYP1A2 403/4885ALDH1A1 637/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.