SCHEMBL26044456

SCHEMBL26044456

CCCCCCCCCCCCCCCC(=O)NCCOCCNC(=O)CC[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)OC(C)(C)C

nearest known ligand 0.60

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ TLR2 O60603 7/20 0.60
▸ BCHE P06276 2/20 0.48
▸ ACHE P22303 2/20 0.48
▸ KMT2A Q03164 1/20 0.45
▸ TNF P01375 2/20 0.43
▸ MDM2 Q00987 1/20 0.42
▸ TLR1 Q15399 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23447164 0.91 TLR2 (0.52) TLR2BCHEACHEMDM2
SCHEMBL16048760 0.90 TLR2 (0.51) TLR2BCHEACHEKMT2AMDM2
SCHEMBL16048758 0.90 TLR2 (0.51) TLR2BCHEACHEKMT2AMDM2
SCHEMBL27153081 0.89 TLR2 (0.50) TLR2KMT2AMDM2
SCHEMBL30771460 0.89 TLR2 (0.50) TLR2KMT2AMDM2
SCHEMBL30771405 0.89 TLR2 (0.50) TLR2KMT2AMDM2
SCHEMBL31296168 0.89 TLR2 (0.50) TLR2KMT2AMDM2
SCHEMBL30771499 0.89 TLR2 (0.50) TLR2KMT2AMDM2
SCHEMBL25845385 0.89 TLR2 (0.54) TLR2BCHEACHEKMT2AMDM2
SCHEMBL26044431 0.89 TLR2 (0.56) TLR2BCHEACHEKMT2ATNF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230265429-A1 SKELETAL MUSCLE DELIVERY PLATFORMS AND METHODS OF USE THEREOF Arrowhead Pharmaceuticals, Inc. 2023-08-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230265429-A1 SKELETAL MUSCLE DELIVERY PLATFORMS AND METHODS OF USE THEREOF MUSK, MYLK2, TNNC1 TLR2 3599/4885BCHE 3578/4885ACHE 3139/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback