Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 8/20 | 0.41 |
| ▸ | NAALAD2 | Q9Y3Q0 | 4/20 | 0.41 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.41 |
| ▸ | GGH | Q92820 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10308573 | 1.00 | FOLH1 (0.41) | FOLH1NAALAD2RIMKLAGGHCYP1A2 | |
| SCHEMBL12249240 | 0.83 | KISS1R (0.32) | FOLH1ANPEPENPEP | |
| SCHEMBL27437901 | 0.82 | NOD1 (0.33) | NOD1 | |
| SCHEMBL18882590 | 0.82 | FOLH1 (0.40) | FOLH1NAALAD2RIMKLAGGHCYP1A2 | |
| SCHEMBL20668143 | 0.82 | FOLH1 (0.40) | FOLH1NAALAD2RIMKLAGGHCYP1A2 | |
| SCHEMBL162037 | 0.80 | FOLH1 (0.61) | FOLH1NAALAD2RIMKLAGGHCYP1A2 | |
| SCHEMBL180085 | 0.80 | FOLH1 (0.61) | FOLH1NAALAD2RIMKLAGGHCYP1A2 | |
| SCHEMBL162038 | 0.80 | FOLH1 (0.61) | FOLH1NAALAD2RIMKLAGGHCYP1A2 | |
| SCHEMBL31599178 | 0.80 | FOLH1 (0.61) | FOLH1NAALAD2RIMKLAGGHCYP1A2 | |
| SCHEMBL24313096 | 0.80 | FOLH1 (0.42) | FOLH1NAALAD2RIMKLAGGHALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023156434-A1 | COMBINATION THERAPIES FOR TREATMENT OF CANCER COMPRISING B7-H4 ANTIBODY DRUG CONJUGATE | MEDIMMUNE LIMITED (GB) | 2023-08-24 | — | — | WO | disclosed |