SCHEMBL26044941

SCHEMBL26044941

CCCOc1ccc(-c2ccc(-c3ccc(CC)cc3)c(F)c2F)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 7/20 0.44
LMNA P02545 4/20 0.44
ALDH1A1 P00352 4/20 0.44
MAPT P10636 4/20 0.44
HPGD P15428 3/20 0.44
L3MBTL1 Q9Y468 4/20 0.43
KDM4E B2RXH2 4/20 0.43
RAB9A P51151 4/20 0.43
NPC1 O15118 3/20 0.43
PTPN7 P35236 1/20 0.42
DUSP3 P51452 1/20 0.42
ACACB O00763 2/20 0.41
ACACA Q13085 2/20 0.41
LTA4H P09960 1/20 0.41
HSD17B10 Q99714 2/20 0.41
HTT P42858 1/20 0.41
MAPK1 P28482 2/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2C19 P33261 1/20 0.40
KMT2A Q03164 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26044944 0.94 LMNA (0.47) SMN1; SMN2LMNAALDH1A1MAPTHPGD
SCHEMBL9495965 0.89 PTPN11 (0.49) SMN1; SMN2LMNAALDH1A1MAPTHPGD
SCHEMBL9493822 0.89 LMNA (0.49) SMN1; SMN2LMNAALDH1A1MAPTL3MBTL1
SCHEMBL9563905 0.88 RARB (0.50) SMN1; SMN2LMNAALDH1A1MAPTHPGD
SCHEMBL9563718 0.88 ALDH1A1 (0.48) SMN1; SMN2LMNAALDH1A1MAPTL3MBTL1
SCHEMBL24025302 0.87 NQO1 (0.48) SMN1; SMN2LMNAALDH1A1MAPTHPGD
SCHEMBL26044942 0.86 LMNA (0.49) SMN1; SMN2LMNAALDH1A1MAPTL3MBTL1
SCHEMBL25693797 0.86 CSNK2A1 (0.39) SMN1; SMN2ALDH1A1MAPTKDM4EACACB
SCHEMBL9564006 0.85 FFAR1 (0.47) SMN1; SMN2LMNAALDH1A1MAPTHPGD
SCHEMBL9563761 0.85 NQO1 (0.47) SMN1; SMN2LMNAALDH1A1MAPTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230265345-A1 LIQUID CRYSTAL COMPOSITION CONTAINING POLYMERIZABLE COMPOUND AND APPLICATION OF LIQUID CRYSTAL COMPOSITION BEIJING BAYI SPACE LCD TECHNOLOGY CO., LTD. (CN) 2023-08-24 US disclosed