SCHEMBL1330864

SCHEMBL1330864

O=C1c2ccccc2C(=O)N1[13CH2]Cl

nearest known ligand 0.54

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.54
CA9 Q16790 2/20 0.54
GLS O94925 1/20 0.54
CASP3 P42574 3/20 0.53
ALDH1A1 P00352 2/20 0.50
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
GSK3B P49841 1/20 0.47
DRD3 P35462 1/20 0.47
ELANE P08246 1/20 0.47
MEN1 O00255 1/20 0.47
PKM P14618 1/20 0.47
KMT2A Q03164 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31402 1.00 CA12 (0.54) CA12CA9GLSCASP3ALDH1A1
SCHEMBL31643071 1.00 CA12 (0.54) CA12CA9GLSCASP3ALDH1A1
SCHEMBL2359299 0.85 CASP3 (0.46) CA12CA9GLSCASP3ALDH1A1
SCHEMBL2296434 0.81 GLS (0.61) GLSCASP3ALDH1A1
SCHEMBL29750183 0.81 GLS (0.61) GLSCASP3ALDH1A1
SCHEMBL10795642 0.81 CYP1B1 (0.67) ALDH1A1MEN1KMT2A
SCHEMBL6699936 0.79 GLS (0.71) CA12CA9GLSCASP3
SCHEMBL2604740 0.79 CA12 (0.58) CA12CA9GLSCASP3ALDH1A1
SCHEMBL31622484 0.78 MAPT (0.62) GLSMEN1KMT2A
SCHEMBL5312972 0.78 MAPT (0.62) GLSMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9673030-B2 Computer readable storage mediums, methods and systems for normalizing chemical profiles in biological or medical samples detected by mass spectrometry EMORY UNIVERSITY (US) 2017-06-06 US disclosed
US-20110282587-A1 COMPUTER READABLE STORAGE MEDIUMS, METHODS AND SYSTEMS FOR NORMALIZING CHEMICAL PROFILES IN BIOLOGICAL OR MEDICAL SAMPLES DETECTED BY MASS SPECTROMETRY EMORY UNIVERSITY (US) 2011-11-17 US disclosed