SCHEMBL26048313

SCHEMBL26048313

C/C=C\Cn1c(=O)n(CC)c(=O)n(CCC[SiH3])c1=O

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.38
MAPK1 P28482 2/20 0.33
GSK3A P49840 2/20 0.31
GSK3B P49841 2/20 0.31
CYP3A4 P08684 1/20 0.31
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
HPGD P15428 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11178702 0.82 GAA (0.45) GAAMAPK1CYP3A4KDM4EALDH1A1
SCHEMBL11174859 0.81 GAA (0.44) GAAMAPK1CYP3A4KDM4EALDH1A1
SCHEMBL11177882 0.81 GAA (0.44) GAAMAPK1CYP3A4KDM4EALDH1A1
SCHEMBL11182708 0.78 GAA (0.44) GAAMAPK1CYP3A4KDM4EALDH1A1
SCHEMBL11178767 0.70 GAA (0.39) GAAMAPK1CYP3A4KDM4EALDH1A1
SCHEMBL28130251 0.69 GAA (0.50) GAAMAPK1CYP3A4KDM4EALDH1A1
SCHEMBL26048308 0.67 HTT (0.36) GSK3B
SCHEMBL23075168 0.66 RGS4 (0.31)
SCHEMBL10014291 0.65 ADORA2B (0.47) MAPK1GSK3AGSK3BCYP3A4ALDH1A1
SCHEMBL2446004 0.65 GSK3B (0.48) GAAGSK3AGSK3BCYP3A4KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023157943-A1 SILICON-CONTAINING RESIST UNDERLAYER FILM FORMING COMPOSITION HAVING UNSATURATED BOND AND CYCLIC STRUCTURE 日産化学株式会社 2023-08-24 WO disclosed