Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 9/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 9/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 13/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | MC4R | P32245 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22481288 | 0.83 | ADRB2 (0.56) | CYP3A4MAPK1CYP2D6TSHRCYP1A2 | |
| SCHEMBL24065695 | 0.82 | CYP3A4 (0.44) | CYP3A4MAPK1CYP2D6TSHRHIF1A | |
| SCHEMBL24065670 | 0.80 | CYP3A4 (0.42) | CYP3A4MAPK1CYP2D6TSHRHIF1A | |
| SCHEMBL22481180 | 0.67 | HIF1A (0.56) | CYP3A4CYP2D6TSHRHIF1ACYP1A2 | |
| SCHEMBL22480735 | 0.67 | HIF1A (0.56) | CYP3A4CYP2D6TSHRHIF1ACYP1A2 | |
| SCHEMBL22493460 | 0.67 | HIF1A (0.56) | CYP3A4CYP2D6TSHRHIF1ACYP1A2 | |
| SCHEMBL9781951 | 0.66 | ADRB2 (0.58) | CYP3A4MAPK1CYP2D6TSHRHIF1A | |
| SCHEMBL7145334 | 0.66 | ADRB2 (0.63) | CYP3A4MAPK1CYP2D6TSHRHIF1A | |
| SCHEMBL7145339 | 0.66 | ADRB2 (0.63) | CYP3A4MAPK1CYP2D6TSHRHIF1A | |
| SCHEMBL11168968 | 0.65 | NR1H4 (0.44) | ADRB1ADRB3ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230263749-A1 | COMPOSITIONS AND METHODS FOR IMPROVING NEUROLOGICAL DISEASES AND DISORDERS | CURASEN THERAPEUTICS, INC. | 2023-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230263749-A1 | COMPOSITIONS AND METHODS FOR IMPROVING NEUROLOGICAL DISEASES AND DISORDERS | ADRA2A, SNCA, ADRA1A | CYP3A4 4109/4885MAPK1 3765/4885CYP2D6 3407/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.