SCHEMBL260495

SCHEMBL260495

Brc1ccc(C=Cc2ccccc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.56
NFE2L2 Q16236 1/20 0.56
CYP19A1 P11511 1/20 0.56
MAOA P21397 1/20 0.56
CYP1B1 Q16678 1/20 0.55
ALDH1A1 P00352 3/20 0.53
TDP1 Q9NUW8 1/20 0.53
RAB9A P51151 3/20 0.52
HPGD P15428 2/20 0.52
KDM4E B2RXH2 1/20 0.52
CYP2C19 P33261 1/20 0.52
RELA Q04206 2/20 0.50
MAPK1 P28482 1/20 0.50
HDAC1 Q13547 1/20 0.50
TRPA1 O75762 1/20 0.50
G6PD P11413 1/20 0.48
KMT2A Q03164 3/20 0.48
MEN1 O00255 2/20 0.48
NPC1 O15118 1/20 0.47
RXFP1 Q9HBX9 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL622876 1.00 MAOB (0.56) MAOBNFE2L2CYP19A1MAOACYP1B1
SCHEMBL2947332 1.00 MAOB (0.56) MAOBNFE2L2CYP19A1MAOACYP1B1
SCHEMBL14491222 1.00 MAOB (0.56) MAOBNFE2L2CYP19A1MAOACYP1B1
SCHEMBL10539842 0.93 ALDH1A1 (0.64) MAOBNFE2L2CYP19A1MAOACYP1B1
SCHEMBL10042632 0.93 ALDH1A1 (0.64) MAOBNFE2L2CYP19A1MAOACYP1B1
SCHEMBL9973880 0.90 MAOB (0.70) MAOBNFE2L2CYP19A1MAOACYP1B1
SCHEMBL11692031 0.90 MAOB (0.70) MAOBNFE2L2CYP19A1MAOACYP1B1
SCHEMBL2577996 0.88 ALDH1A1 (0.61) CYP1B1ALDH1A1RAB9AHPGDKDM4E
SCHEMBL9679607 0.88 ALDH1A1 (0.61) CYP1B1ALDH1A1RAB9AHPGDKDM4E
SCHEMBL9679616 0.88 ALDH1A1 (0.61) CYP1B1ALDH1A1RAB9AHPGDKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 143 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119735767-A Method for preparing polyisobutene and block copolymer thereof by Fe system coinitiator 北京石油化工学院 2025-04-01 CN claimed
CN-114539079-A Diamine monomer containing tetraphenylethylene-diarylamine structure, preparation method and application of diamine monomer in super-stable electrochromic material 吉林大学 2022-05-27 CN claimed
US-7105714-B2 Phosphonium salt formation from a phosphine and a carbonium compound, ball milling to form the phosphorus ylide, phosphorylation of an aldehyde or ketone; one pot process; improved catalyst selectivity, efficiency; low temperature, industrial scale IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2006-09-12 US claimed
US-20040260128-A1 Solvent-free mechanochemical preparation of phosphonium salts, phosphorus ylides, and olefins IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. 2004-12-23 US claimed
US-20030176740-A1 Solvent-free mechanochemical preparation of phosphonium salts, phosphorus ylides, and olefins IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. 2003-09-18 US claimed
WO-2003066548-A2 SOLVENT-FREE MECHANOCHEMICAL PREPARATION OF PHOSPHONIUM SALTS, PHOSPHORUS YLIDES, AND OLEFINS IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2003-08-14 WO claimed
CN-122079722-A Triphenylamine-mediated isomerization method for photocatalytic olefins E to Z 2026-05-26 CN disclosed
CN-119735767-A Method for preparing polyisobutene and block copolymer thereof by Fe system coinitiator 北京石油化工学院 2025-04-01 CN disclosed
CN-119263992-A Novel compound for capping layer and organic light-emitting element comprising same 东进世美肯株式会社 2025-01-07 CN disclosed
CN-119080719-A Preparation method of polysubstituted olefin epoxy compound 广西科技大学 2024-12-06 CN disclosed
US-20240360156-A1 HETEROCYCLIC COMPOUND AND USE THEREOF TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2024-10-31 US disclosed
US-20240027901-A1 PHOTOACID GENERATOR, AND PHOTOSENSITIVE COMPOSITION USING SAME SAN-APRO LTD. (JP) 2024-01-25 US disclosed
EP-4261214-A1 PHOTOACID GENERATOR, AND PHOTOSENSITIVE COMPOSITION USING SAME San-Apro Ltd. (JP) 2023-10-18 EP disclosed
US-5593486-A Photochromic hot melt ink compositions XEROX CORPORATION (US) 1997-01-14 US disclosed
US-5551973-A LIQUID CRYSTAL GEL PHASE, MICROEMULSION PHASE XEROX CORPORATION (US) 1996-09-03 US disclosed
EP-0596057-A1 QUINUCLIDINE DERIVATIVES AS SQUALENE SYNTHASE INHIBITORS ZENECA LIMITED (GB) 1994-05-11 EP disclosed
WO-1993021183-A1 QUINUCLIDINE DERIVATIVES AS SQUALENE SYNTHASE INHIBITORS ZENECA LIMITED (GB) 1993-10-28 WO disclosed
EP-0041043-B1 PROCESS FOR THE PREPARATION OF DERIVATIVES OF ALKENYL BENZENE OR ALKENYL NAPHTHALENE CIBA-GEIGY AG (CH) 1983-11-09 EP disclosed
US-4335055-A Process for the preparation of alkenylbenzene derivatives or alkenylnaphthalene derivatives CIBA-GEIGY CORPORATION (US) 1982-06-15 US disclosed
EP-0041043-A1 Process for the preparation of derivatives of alkenyl benzene or alkenyl naphthalene CIBA-GEIGY AG (CH) 1981-12-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240360156-A1 HETEROCYCLIC COMPOUND AND USE THEREOF GRIN1, GRIN2C, GRIN2A MAOB 258/4885NFE2L2 2918/4885CYP19A1 985/4885
US-20240027901-A1 PHOTOACID GENERATOR, AND PHOTOSENSITIVE COMPOSITION USING SAME ATIC, MAP1LC3C, TYR MAOB 1035/4885NFE2L2 2519/4885CYP19A1 3266/4885
US-20040260128-A1 Solvent-free mechanochemical preparation of phosphonium salts, phosphorus ylides, and olefins CCR4, CCR1, CCR6 MAOB 4881/4885NFE2L2 4005/4885CYP19A1 4658/4885
US-20030176740-A1 Solvent-free mechanochemical preparation of phosphonium salts, phosphorus ylides, and olefins CCR4, CCR1, CCR6 MAOB 4881/4885NFE2L2 4005/4885CYP19A1 4658/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.