SCHEMBL2947332

SCHEMBL2947332

Brc1ccc(/C=C\c2ccccc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.56
NFE2L2 Q16236 1/20 0.56
CYP19A1 P11511 1/20 0.56
MAOA P21397 1/20 0.56
CYP1B1 Q16678 1/20 0.55
ALDH1A1 P00352 3/20 0.53
TDP1 Q9NUW8 1/20 0.53
RAB9A P51151 3/20 0.52
HPGD P15428 2/20 0.52
KDM4E B2RXH2 1/20 0.52
CYP2C19 P33261 1/20 0.52
RELA Q04206 2/20 0.50
MAPK1 P28482 1/20 0.50
HDAC1 Q13547 1/20 0.50
TRPA1 O75762 1/20 0.50
G6PD P11413 1/20 0.48
KMT2A Q03164 3/20 0.48
MEN1 O00255 2/20 0.48
NPC1 O15118 1/20 0.47
RXFP1 Q9HBX9 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL622876 1.00 MAOB (0.56) MAOBNFE2L2CYP19A1MAOACYP1B1
SCHEMBL260495 1.00 MAOB (0.56) MAOBNFE2L2CYP19A1MAOACYP1B1
SCHEMBL14491222 1.00 MAOB (0.56) MAOBNFE2L2CYP19A1MAOACYP1B1
SCHEMBL10539842 0.93 ALDH1A1 (0.64) MAOBNFE2L2CYP19A1MAOACYP1B1
SCHEMBL10042632 0.93 ALDH1A1 (0.64) MAOBNFE2L2CYP19A1MAOACYP1B1
SCHEMBL9973880 0.90 MAOB (0.70) MAOBNFE2L2CYP19A1MAOACYP1B1
SCHEMBL11692031 0.90 MAOB (0.70) MAOBNFE2L2CYP19A1MAOACYP1B1
SCHEMBL2577996 0.88 ALDH1A1 (0.61) CYP1B1ALDH1A1RAB9AHPGDKDM4E
SCHEMBL9679607 0.88 ALDH1A1 (0.61) CYP1B1ALDH1A1RAB9AHPGDKDM4E
SCHEMBL9679616 0.88 ALDH1A1 (0.61) CYP1B1ALDH1A1RAB9AHPGDKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114713283-B Cobalt nanoparticle high-efficiency selective catalytic system and method for generating (Z) -alkene by reducing alkyne by using same 沈阳药科大学 2024-05-14 CN disclosed
CN-114713283-A Cobalt nanoparticle efficient selective catalytic system and method for reducing alkyne to generate (Z) -olefin by using same 沈阳药科大学 2022-07-08 CN disclosed
US-8911882-B2 Stilbene derivative, light-emitting element, light-emitting device, and electronic device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-12-16 US disclosed
US-8911882-B2 Stilbene derivative, light-emitting element, light-emitting device, and electronic device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-12-16 US disclosed
US-8911882-B2 Stilbene derivative, light-emitting element, light-emitting device, and electronic device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-12-16 US disclosed
US-7758972-B2 Carbazole substituents; light emitting layer between a pair of electrodes, blue light emission with excellent color purity SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-07-20 US disclosed
US-7758972-B2 Carbazole substituents; light emitting layer between a pair of electrodes, blue light emission with excellent color purity SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-07-20 US disclosed
US-7758972-B2 Carbazole substituents; light emitting layer between a pair of electrodes, blue light emission with excellent color purity SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-07-20 US disclosed
US-20080145700-A1 Carbazole substituents; light emitting layer between a pair of electrodes, blue light emission with excellent color purity SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-06-19 US disclosed
US-20080145700-A1 Carbazole substituents; light emitting layer between a pair of electrodes, blue light emission with excellent color purity SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-06-19 US disclosed
US-20080145700-A1 Carbazole substituents; light emitting layer between a pair of electrodes, blue light emission with excellent color purity SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-06-19 US disclosed
US-20080088229-A1 Stilbene Derivative, Light-Emitting Element, Light-Emitting Device, and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2008-04-17 US disclosed
US-20080088229-A1 Stilbene Derivative, Light-Emitting Element, Light-Emitting Device, and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2008-04-17 US disclosed
US-20080088229-A1 Stilbene Derivative, Light-Emitting Element, Light-Emitting Device, and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2008-04-17 US disclosed
WO-2003066548-A2 SOLVENT-FREE MECHANOCHEMICAL PREPARATION OF PHOSPHONIUM SALTS, PHOSPHORUS YLIDES, AND OLEFINS IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2003-08-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080088229-A1 Stilbene Derivative, Light-Emitting Element, Light-Emitting Device, and Electronic Device HSF1, HSPA1B, HSPB1 MAOB 2693/4885NFE2L2 27/4885CYP19A1 104/4885
US-20080145700-A1 Carbazole substituents; light emitting layer between a pair of electrodes, blue light emission with excellent color purity CYP1B1, CYBA, CYP4B1 MAOB 624/4885NFE2L2 538/4885CYP19A1 189/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.