Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 10/20 | 0.43 |
| ▸ | CNR1 | P21554 | 8/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL991661 | 0.86 | MEN1 (0.68) | MEN1KMT2ATDP1MAPK1ALDH1A1 | |
| SCHEMBL991850 | 0.82 | MEN1 (0.73) | MEN1KMT2ATDP1MAPK1ALDH1A1 | |
| SCHEMBL18013744 | 0.82 | TDP1 (0.73) | MEN1KMT2ATDP1MAPTMAPK1 | |
| SCHEMBL11563597 | 0.82 | MEN1 (0.73) | MEN1KMT2ATDP1MAPK1ALDH1A1 | |
| SCHEMBL26049775 | 0.81 | MEN1 (0.54) | MEN1KMT2ATDP1MAPTMAPK1 | |
| SCHEMBL26049789 | 0.81 | MEN1 (0.60) | MEN1KMT2ATDP1CNR2FAAH | |
| SCHEMBL11555708 | 0.81 | MEN1 (0.60) | MEN1KMT2ATDP1MAPK1ALDH1A1 | |
| SCHEMBL11561310 | 0.81 | MEN1 (0.60) | MEN1KMT2ATDP1MAPK1ALDH1A1 | |
| SCHEMBL11554831 | 0.81 | MEN1 (0.71) | MEN1KMT2ATDP1MAPTMAPK1 | |
| SCHEMBL11558044 | 0.81 | MEN1 (0.71) | MEN1KMT2ATDP1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023151898-A1 | TOFA ANALOGUES, SEBUM REDUCTION PREPARATIONS CONTAINING SAID TYPE OF ANALOGUES AND THE COSMETIC AND/OR THERAPEUTIC USE OF SAID TYPE OF ANALOGUES AS AN EFFECTIVE PRINCIPLE FOR REDUCING OR PREVENTING SEBUM | BEIERSDORF AG (DE) | 2023-08-17 | — | — | WO | disclosed |
| WO-2023151897-A1 | TOFA ANALOGUES, SEBUM REDUCTION PREPARATIONS CONTAINING SAID TYPE OF ANALOGUES AND THE COSMETIC AND/OR THERAPEUTIC USE OF SAID TYPE OF ANALOGUES AS AN EFFECTIVE PRINCIPLE FOR REDUCING OR PREVENTING SEBUM | BEIERSDORF AG (DE) | 2023-08-17 | — | — | WO | disclosed |