Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26050252 | 0.74 | GBA1 (0.45) | SMN1; SMN2 | |
| SCHEMBL21618579 | 0.73 | POLB (0.35) | GRM2GRM3 | |
| SCHEMBL16207902 | 0.72 | SMN1; SMN2 (0.36) | SMN1; SMN2 | |
| SCHEMBL26050348 | 0.72 | GBA2 (0.47) | — | |
| SCHEMBL1545232 | 0.71 | GBA1 (0.50) | — | |
| SCHEMBL7700224 | 0.70 | ALDH1A1 (0.43) | SMN1; SMN2 | |
| SCHEMBL7538300 | 0.68 | TACR1 (0.33) | — | |
| SCHEMBL5015303 | 0.66 | GBA1 (0.41) | SMN1; SMN2 | |
| SCHEMBL9340416 | 0.66 | GBA2 (0.42) | SMN1; SMN2S1PR5 | |
| SCHEMBL12616624 | 0.64 | ALDH1A1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192817-A1 | INHIBITORS OF THE MYST FAMILY OF LYSINE ACETYL TRANSFERASES | Isosterix, Inc. (US) | 2023-10-05 | — | — | WO | disclosed |