Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 3/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 2/20 | 0.39 |
| ▸ | WNT1 | P04628 | 1/20 | 0.39 |
| ▸ | CBLB | Q13191 | 2/20 | 0.38 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.38 |
| ▸ | BUB1 | O43683 | 2/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTR1F | P30939 | 1/20 | 0.37 |
| ▸ | BRAF | P15056 | 1/20 | 0.36 |
| ▸ | PIK3C3 | Q8NEB9 | 4/20 | 0.36 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.36 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20069615 | 0.78 | ALDH1A1 (0.52) | PDPK1ALDH1A1 | |
| SCHEMBL25605210 | 0.76 | ALDH1A1 (0.40) | NR3C2ALDH1A1LMNABRAF | |
| SCHEMBL26354202 | 0.76 | KDM4E (0.54) | DYRK1AGSK3BWNT1ALDH1A1 | |
| SCHEMBL20069622 | 0.73 | RAB9A (0.54) | ALDH1A1LMNA | |
| SCHEMBL84076 | 0.72 | L3MBTL1 (0.52) | BRAFPIK3C3MAPKAPK2 | |
| SCHEMBL25605223 | 0.72 | ALDH1A1 (0.62) | ALDH1A1LMNA | |
| SCHEMBL20889610 | 0.71 | NR3C2 (0.57) | NR3C2 | |
| SCHEMBL15627415 | 0.71 | TYK2 (0.52) | GSK3BALDH1A1LMNABRAF | |
| SCHEMBL10199545 | 0.71 | BRAF (0.61) | GSK3BBRAFPIK3C3ABL1 | |
| SCHEMBL12230269 | 0.70 | GCK (0.54) | NR3C2ALDH1A1BRAFABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023150203-A1 | HDAC6 INHIBITORS AND USES THEREOF | EIKONIZO THERAPEUTICS, INC. (US) | 2023-08-10 | — | — | WO | disclosed |