Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21651967 | 0.87 | DRD2 (0.60) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL13696944 | 0.83 | TDP1 (0.53) | NPC1RAB9ASMN1; SMN2LMNATDP1 | |
| SCHEMBL20148061 | 0.81 | RAB9A (0.50) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL20148034 | 0.74 | POLB (0.49) | MEN1KMT2ALMNAPOLBTP53 | |
| SCHEMBL30074425 | 0.71 | TDP1 (0.55) | NPC1RAB9ALMNATDP1POLB | |
| SCHEMBL13212255 | 0.71 | NPC1 (0.50) | NPC1RAB9ASMN1; SMN2LMNATDP1 | |
| SCHEMBL14349967 | 0.71 | SPHK1 (0.48) | NPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL25504420 | 0.70 | KDM4E (0.60) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL20069153 | 0.70 | DRD2 (0.54) | NPC1RAB9ASMN1; SMN2KMT2ALMNA | |
| SCHEMBL25775264 | 0.70 | MAPT (0.53) | NPC1RAB9ASMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023150203-A1 | HDAC6 INHIBITORS AND USES THEREOF | EIKONIZO THERAPEUTICS, INC. (US) | 2023-08-10 | — | — | WO | disclosed |