Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UBE2M | P61081 | 10/20 | 0.44 |
| ▸ | DCUN1D1 | Q96GG9 | 10/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | TPH1 | P17752 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26053265 | 0.90 | HPGD (0.46) | UBE2MDCUN1D1LMNATP53MAPT | |
| SCHEMBL26053584 | 0.89 | TPH1 (0.39) | UBE2MDCUN1D1LMNATP53MAPT | |
| SCHEMBL26054535 | 0.88 | AOC3 (0.39) | UBE2MDCUN1D1LMNATP53MAPT | |
| SCHEMBL26053718 | 0.86 | TP53 (0.45) | UBE2MDCUN1D1LMNATP53MAPT | |
| SCHEMBL26053578 | 0.85 | TPH1 (0.39) | UBE2MDCUN1D1LMNATP53MAPT | |
| SCHEMBL26053581 | 0.85 | TPH1 (0.43) | UBE2MDCUN1D1LMNATP53MAPT | |
| SCHEMBL26053269 | 0.85 | CASP3 (0.44) | UBE2MDCUN1D1LMNATP53MAPT | |
| SCHEMBL26053579 | 0.85 | TPH1 (0.41) | UBE2MDCUN1D1LMNATP53MAPT | |
| SCHEMBL26054199 | 0.85 | HRH4 (0.41) | TPH1 | |
| SCHEMBL31595866 | 0.85 | ALDH1A1 (0.42) | UBE2MDCUN1D1LMNATP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023164237-A1 | COMPOUNDS AND METHODS USEFUL FOR STABILIZING PHENYLALANINE HYDROXYLASE MUTATIONS | AGIOS PHARMACEUTICALS, INC. (US) | 2023-08-31 | — | — | WO | disclosed |