Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 6/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.34 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.34 |
| ▸ | MAP1LC3A | Q9H492 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9579004 | 0.85 | OPRM1 (0.50) | OPRM1OPRD1OPRK1ESR1TAAR1 | |
| SCHEMBL5109630 | 0.80 | TAAR1 (0.57) | OPRM1OPRD1OPRK1TAAR1SLC6A2 | |
| SCHEMBL10284554 | 0.79 | HTR2A (0.43) | OPRK1TAAR1MAOASLC6A2SLC6A4 | |
| SCHEMBL13614169 | 0.78 | OPRM1 (0.45) | OPRM1OPRD1OPRK1SIGMAR1 | |
| SCHEMBL12152346 | 0.78 | OPRM1 (0.45) | OPRM1OPRD1OPRK1TAAR1MAOA | |
| SCHEMBL12510850 | 0.78 | OPRM1 (0.45) | OPRM1OPRD1OPRK1ESR1 | |
| SCHEMBL3056983 | 0.78 | TAAR1 (0.59) | OPRM1OPRD1OPRK1TAAR1SLC6A2 | |
| SCHEMBL11949748 | 0.77 | CNR1 (0.42) | OPRM1OPRD1OPRK1TAAR1SIGMAR1 | |
| SCHEMBL2428599 | 0.76 | MAOA (0.59) | OPRM1OPRD1OPRK1TAAR1MAOA | |
| SCHEMBL104012 | 0.76 | OPRK1 (0.70) | OPRM1OPRD1OPRK1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11739121-B2 | EPHA2 agonists and uses thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11739121-B2 | EPHA2 agonists and uses thereof | EPHA2, EPHB2, EPHA6 | OPRM1 1446/4885OPRD1 3010/4885OPRK1 2574/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.