Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 7/20 | 0.40 |
| ▸ | SPR | P35270 | 4/20 | 0.35 |
| ▸ | UBE2M | P61081 | 3/20 | 0.35 |
| ▸ | DCUN1D1 | Q96GG9 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | TPH1 | P17752 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31596064 | 1.00 | GRM5 (0.40) | GRM5SPRUBE2MDCUN1D1ALDH1A1 | |
| SCHEMBL31595708 | 0.90 | TPH1 (0.38) | GRM5UBE2MDCUN1D1TPH1 | |
| SCHEMBL26055113 | 0.86 | SMN1; SMN2 (0.37) | GRM5UBE2MDCUN1D1ALDH1A1TPH1 | |
| SCHEMBL31595722 | 0.85 | UBE2M (0.35) | SPRUBE2MDCUN1D1ALDH1A1GAA | |
| SCHEMBL26055111 | 0.85 | UBE2M (0.35) | SPRUBE2MDCUN1D1ALDH1A1GAA | |
| SCHEMBL26054887 | 0.84 | UBE2M (0.39) | SPRUBE2MDCUN1D1ALDH1A1GAA | |
| SCHEMBL31596204 | 0.83 | GRM5 (0.36) | GRM5UBE2MDCUN1D1ALDH1A1TPH1 | |
| SCHEMBL26055110 | 0.83 | UBE2M (0.38) | SPRUBE2MDCUN1D1ALDH1A1GAA | |
| SCHEMBL26054762 | 0.83 | GRM5 (0.36) | GRM5UBE2MDCUN1D1TPH1 | |
| SCHEMBL26053863 | 0.83 | UBE2M (0.44) | UBE2MDCUN1D1ALDH1A1GAAGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023164237-A1 | COMPOUNDS AND METHODS USEFUL FOR STABILIZING PHENYLALANINE HYDROXYLASE MUTATIONS | AGIOS PHARMACEUTICALS, INC. (US) | 2023-08-31 | — | — | WO | disclosed |