Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UBE2M | P61081 | 3/20 | 0.35 |
| ▸ | DCUN1D1 | Q96GG9 | 3/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | TPH1 | P17752 | 3/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26054885 | 0.86 | TPH1 (0.35) | UBE2MDCUN1D1AOC3TP53MAPT | |
| SCHEMBL26053718 | 0.85 | TP53 (0.45) | UBE2MDCUN1D1AOC3TP53MAPT | |
| SCHEMBL26054200 | 0.85 | LMNA (0.35) | UBE2MDCUN1D1AOC3TP53MAPT | |
| SCHEMBL31596204 | 0.84 | GRM5 (0.36) | UBE2MDCUN1D1AOC3HSD11B1ALDH1A1 | |
| SCHEMBL26054888 | 0.84 | AOC3 (0.33) | UBE2MDCUN1D1AOC3HSD11B1ALDH1A1 | |
| SCHEMBL26054880 | 0.84 | AOC3 (0.34) | UBE2MDCUN1D1AOC3MAPTHSD11B1 | |
| SCHEMBL26054975 | 0.83 | UBE2M (0.33) | UBE2MDCUN1D1AOC3HSD11B1TPH1 | |
| SCHEMBL26053991 | 0.83 | GRM5 (0.34) | UBE2MDCUN1D1AOC3HSD11B1TPH1 | |
| SCHEMBL31596183 | 0.83 | UBE2M (0.32) | UBE2MDCUN1D1AOC3HSD11B1TPH1 | |
| SCHEMBL26055260 | 0.83 | AOC3 (0.33) | UBE2MDCUN1D1AOC3HSD11B1TPH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250171438-A1 | COMPOUNDS AND METHODS USEFUL FOR STABILIZING PHENYLALANINE HYDROXYLASE MUTATIONS | AGIOS PHARMACEUTICALS, INC. | 2025-05-29 | — | — | US | disclosed |
| WO-2023164237-A1 | COMPOUNDS AND METHODS USEFUL FOR STABILIZING PHENYLALANINE HYDROXYLASE MUTATIONS | AGIOS PHARMACEUTICALS, INC. (US) | 2023-08-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250171438-A1 | COMPOUNDS AND METHODS USEFUL FOR STABILIZING PHENYLALANINE HYDROXYLASE MUTATIONS | PAH, KDM8, PHF8 | UBE2M 4437/4885DCUN1D1 2773/4885AOC3 2995/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.