SCHEMBL26061014

SCHEMBL26061014

CC1(C)c2ccccc2-c2c(N(c3ccccc3)c3cccc4ccc5c6ccccc6ccc5c34)cccc21

nearest known ligand 0.34

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.34
CYP1A2 P05177 2/20 0.34
HPGD P15428 2/20 0.34
HSD17B10 Q99714 2/20 0.34
THRB P10828 1/20 0.34
ERBB2 P04626 1/20 0.33
FYN P06241 1/20 0.33
MAOA P21397 1/20 0.33
ACHE P22303 1/20 0.33
AHR P35869 1/20 0.33
TSHR P16473 1/20 0.33
MAPK1 P28482 1/20 0.33
CASP1 P29466 1/20 0.33
HIF1A Q16665 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
HPRT1 P00492 2/20 0.33
SIGMAR1 Q99720 2/20 0.32
PDK2 Q15119 1/20 0.32
TYMS P04818 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26061023 0.91 ENPP3 (0.32) ALDH1A1CYP1A2HPGDHSD17B10THRB
SCHEMBL26061084 0.90 ALDH1A1 (0.32) ALDH1A1CYP1A2HPGDHSD17B10THRB
SCHEMBL26059433 0.90 HPRT1 (0.35) HPRT1SIGMAR1PDK2
SCHEMBL26061072 0.89 CYP1A2 (0.33) ALDH1A1CYP1A2HPGDHSD17B10THRB
SCHEMBL26061021 0.88 LPL (0.31) ALDH1A1CYP1A2HPGDHSD17B10ERBB2
SCHEMBL26534692 0.88 ALDH1A1 (0.33) ALDH1A1CYP1A2HPGDHSD17B10ERBB2
SCHEMBL26060540 0.88 SOS1 (0.33) ALDH1A1CYP1A2HPGDHSD17B10ERBB2
SCHEMBL26060069 0.88 HPRT1 (0.33) ALDH1A1CYP1A2HPGDHSD17B10ERBB2
SCHEMBL17081217 0.87 PDK2 (0.31) PDK2
SCHEMBL26060943 0.87 HPRT1 (0.33) ALDH1A1CYP1A2HPGDMAPK1HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4235829-A1 ORGANIC LIGHT-EMITTING DEVICE Lg Chem, Ltd. (KR) 2023-08-30 EP disclosed