Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.38 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.38 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.38 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | HNF4A | P41235 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12864298 | 0.92 | BCAT2 (0.44) | BCAT2MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL13191852 | 0.87 | BCAT2 (0.49) | BCAT2MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL12187086 | 0.87 | BCAT2 (0.49) | BCAT2MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL10054058 | 0.82 | ESR1 (0.42) | MAPK13MAPK12MAPK11MAPK14MEN1 | |
| SCHEMBL13649845 | 0.81 | PDK2 (0.40) | THRBTDP1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10053610 | 0.81 | PDK2 (0.40) | THRBTDP1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2606066 | 0.79 | PDK2 (0.41) | THRBTDP1PDK2ATM | |
| SCHEMBL134291 | 0.78 | BCAT2 (0.59) | BCAT2MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL12864302 | 0.77 | PDK2 (0.46) | THRBTDP1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1167840 | 0.76 | TDP1 (0.52) | THRBTDP1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2260023-B1 | FLUORENE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2012-04-25 | — | — | EP | disclosed |