Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24283376 | 0.86 | SKP2 (0.39) | ALOX5CYP1A2MAPTNPC1RAB9A | |
| SCHEMBL19631221 | 0.81 | SLC6A2 (0.47) | TRPA1CYP1A2CYP2A6KIF11SLC6A2 | |
| SCHEMBL575394 | 0.78 | SLC6A2 (0.41) | TRPA1ALOX5PTGS1PTGS2PDE2A | |
| SCHEMBL575559 | 0.78 | TRPA1 (0.41) | TRPA1ALOX5PTGS1PTGS2PDE2A | |
| SCHEMBL11697189 | 0.77 | ALOX5 (0.31) | ALOX5PTGS1PTGS2ALDH1A1MAPT | |
| SCHEMBL11697185 | 0.77 | ALOX5 (0.31) | ALOX5PTGS1PTGS2ALDH1A1MAPT | |
| SCHEMBL7767017 | 0.76 | HAO1 (0.40) | PTGS1PTGS2CYP1A2CYP2A6SLC6A4 | |
| SCHEMBL12303991 | 0.76 | TRPA1 (0.40) | TRPA1ALOX5PTGS1PTGS2PDE2A | |
| SCHEMBL19431333 | 0.75 | KDM4E (0.38) | TRPA1CYP1A2CYP2A6ALDH1A1MAPT | |
| SCHEMBL27353332 | 0.75 | TRPA1 (0.39) | TRPA1ALOX5PTGS1PTGS2PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3672958-B1 | ANNULATED GLYCOSIDASE INHIBITORS | ASCENEURON SA (CH) | 2023-08-02 | — | — | EP | disclosed |