Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | HTR1A | P08908 | 7/20 | 0.36 |
| ▸ | HTR3A | P46098 | 7/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23795423 | 0.83 | LMNA (0.39) | TP53TDP1LMNAHPGDMEN1 | |
| SCHEMBL20647862 | 0.81 | TP53 (0.47) | HAO1TP53TDP1HTR1AHTR3A | |
| SCHEMBL21553822 | 0.79 | ALDH1A1 (0.31) | HPGDMAPTKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL29543901 | 0.79 | ALDH1A1 (0.31) | HPGDMAPTKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL26062395 | 0.76 | TRPA1 (0.35) | LMNAGAAMAPTALOX12HSD17B10 | |
| SCHEMBL13840027 | 0.75 | NPC1 (0.53) | TP53TDP1LMNAHPGDMEN1 | |
| SCHEMBL1145702 | 0.75 | HAO1 (0.43) | HAO1TP53TDP1HTR1AHTR3A | |
| SCHEMBL29475022 | 0.74 | HAO1 (0.55) | HAO1TP53TDP1HTR1AHTR3A | |
| SCHEMBL76793 | 0.74 | HAO1 (0.55) | HAO1TP53TDP1HTR1AHTR3A | |
| SCHEMBL29411684 | 0.74 | NPC1 (0.50) | HAO1TP53TDP1HTR1AHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019157050-A1 | CERTAIN (2S)-N-[(1S)-1-CYANO-2-PHENYLETHYL]-1,4-OXAZEPANE-2-CARBOXAMIDES FOR TREATING ANCA ASSOCIATED VASCULITIDES | INSMED INCORPORATED (US) | 2019-08-15 | — | — | WO | disclosed |
| EP-2791137-B1 | PYRAZOLOPYRIDINE DERIVATIVES, PREPARATION PROCESS THEREFOR AND THERAPEUTIC USE THEREOF | SANOFI SA (FR) | 2019-01-23 | — | — | EP | disclosed |
| EP-0711813-B1 | Antifouling coating composition | HITACHI CHEMICAL CO LTD (JP) | 2001-07-25 | — | — | EP | disclosed |
| US-5773508-A | BIODEGRADABLE POLYMER OF ADDITION COPOLYMERS FOR PROTECTIVE COATINGS | HITACHI CHEMICAL COMPANY, LTD. (JP) | 1998-06-30 | — | — | US | disclosed |
| EP-0711813-A2 | Coating varnish composition and antifouling coating composition | Hitachi Chemical Co., Ltd. (JP) | 1996-05-15 | — | — | EP | disclosed |