SCHEMBL26063161

SCHEMBL26063161

Cc1cnc(SCCCCCCCCCCCO)[nH]c1=O

nearest known ligand 0.56

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDM6B O15054 5/20 0.56
KDM4A O75164 5/20 0.56
KDM4D Q6B0I6 5/20 0.56
KDM3B Q7LBC6 5/20 0.56
HIF1AN Q9NWT6 5/20 0.56
KDM5B Q9UGL1 5/20 0.56
KDM2A Q9Y2K7 5/20 0.56
GAA P10253 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
PLA2G7 Q13093 10/20 0.47
GPR84 Q9NQS5 1/20 0.44
CYP1A2 P05177 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
XDH P47989 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26039915 0.84 KDM6B (0.65) KDM6BKDM4AKDM4DKDM3BHIF1AN
SCHEMBL26063190 0.82 ALDH1A1 (0.45) KDM6BKDM4AKDM4DKDM3BHIF1AN
SCHEMBL24211701 0.79 KDM6B (0.47) KDM6BKDM4AKDM4DKDM3BHIF1AN
SCHEMBL24211562 0.79 KDM6B (0.47) KDM6BKDM4AKDM4DKDM3BHIF1AN
SCHEMBL26063918 0.78 KDM6B (0.46) KDM6BKDM4AKDM4DKDM3BHIF1AN
SCHEMBL26063772 0.77 KDM6B (0.46) KDM6BKDM4AKDM4DKDM3BHIF1AN
SCHEMBL26063788 0.76 KDM6B (0.47) KDM6BKDM4AKDM4DKDM3BHIF1AN
SCHEMBL8752059 0.75 KDM6B (0.42) KDM6BKDM4AKDM4DKDM3BHIF1AN
SCHEMBL26064122 0.74 ALDH1A1 (0.41) KDM6BKDM4AKDM4DKDM3BHIF1AN
SCHEMBL24211542 0.72 GPR84 (0.75) GAASMN1; SMN2GPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230273456-A1 OPTICALLY ACTIVE DEVICES JOHNSON & JOHNSON SURGICAL VISION INC (US) 2023-08-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230273456-A1 OPTICALLY ACTIVE DEVICES PDE6C, PDE6D, PDE6A KDM6B 1786/4885KDM4A 2430/4885KDM4D 1966/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.