Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | KDM6B | O15054 | 8/20 | 0.43 |
| ▸ | KDM4A | O75164 | 8/20 | 0.43 |
| ▸ | KDM4D | Q6B0I6 | 8/20 | 0.43 |
| ▸ | HIF1AN | Q9NWT6 | 8/20 | 0.43 |
| ▸ | KDM2A | Q9Y2K7 | 8/20 | 0.43 |
| ▸ | KDM5B | Q9UGL1 | 6/20 | 0.43 |
| ▸ | KDM3B | Q7LBC6 | 6/20 | 0.43 |
| ▸ | DAO | P14920 | 6/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20060568 | 0.84 | MAPK1 (0.61) | ALDH1A1MAPK1KDM4EKDM6BKDM4A | |
| SCHEMBL26063161 | 0.82 | KDM6B (0.56) | KDM6BKDM4AKDM4DHIF1ANKDM2A | |
| SCHEMBL26064122 | 0.80 | ALDH1A1 (0.41) | ALDH1A1MAPK1KDM4EKDM6BKDM4A | |
| SCHEMBL26039915 | 0.78 | KDM6B (0.65) | ALDH1A1KDM4EKDM6BKDM4AKDM4D | |
| SCHEMBL5301134 | 0.78 | ALDH1A1 (0.52) | ALDH1A1MAPK1KDM4E | |
| SCHEMBL3577936 | 0.77 | KDM6B (0.58) | ALDH1A1MAPK1KDM4EKDM6BKDM4A | |
| SCHEMBL8752059 | 0.76 | KDM6B (0.42) | ALDH1A1MAPK1KDM4EKDM6BKDM4A | |
| SCHEMBL26063177 | 0.74 | ALDH1A1 (0.43) | ALDH1A1MAPK1KDM4EKDM6BKDM4A | |
| SCHEMBL4953030 | 0.73 | PLA2G7 (0.62) | ALDH1A1KDM6BKDM4AKDM4DHIF1AN | |
| SCHEMBL26063199 | 0.71 | KDM6B (0.46) | ALDH1A1MAPK1KDM4EKDM6BKDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230273456-A1 | OPTICALLY ACTIVE DEVICES | JOHNSON & JOHNSON SURGICAL VISION INC (US) | 2023-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230273456-A1 | OPTICALLY ACTIVE DEVICES | PDE6C, PDE6D, PDE6A | ALDH1A1 277/4885MAPK1 3249/4885KDM4E 3198/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.