Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EBP | Q15125 | 6/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | SLC2A2 | P11168 | 1/20 | 0.35 |
| ▸ | SLC2A3 | P11169 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26065137 | 0.89 | NAMPT (0.38) | KCNH2 | |
| SCHEMBL26066123 | 0.87 | EBP (0.41) | EBPKCNH2TPSAB1CNR2PTGS1 | |
| SCHEMBL25369913 | 0.86 | EBP (0.34) | EBPKCNH2SLC2A1SLC2A2SLC2A3 | |
| SCHEMBL26066102 | 0.81 | MLNR (0.36) | EBPKCNH2TPSAB1PTGS1PTGS2 | |
| SCHEMBL25371509 | 0.81 | TGFBR1 (0.33) | EBPSLC2A1SLC2A2SLC2A3PSEN1 | |
| SCHEMBL26066151 | 0.80 | EBP (0.41) | EBPKCNH2TPSAB1CNR2 | |
| SCHEMBL26066246 | 0.79 | PSEN1 (0.51) | EBPKCNH2TPSAB1PSEN1PSEN2 | |
| SCHEMBL26066195 | 0.76 | CTSK (0.38) | KCNH2TPSAB1 | |
| SCHEMBL26066193 | 0.76 | PSEN1 (0.42) | EBPKCNH2PSEN1PSEN2APH1B | |
| SCHEMBL26065497 | 0.76 | EBP (0.39) | EBPKCNH2TPSAB1SLC2A1SLC2A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023164063-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | BIOGEN MA INC. (US) | 2023-08-31 | — | — | WO | disclosed |