SCHEMBL25369913

SCHEMBL25369913

O=S(=O)(c1cc(C(F)(F)F)nn1CC1CC1)N1CC2(CN(CC3CCOCC3)C2)C1

nearest known ligand 0.34

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ EBP Q15125 6/20 0.34
▸ SLC2A1 P11166 1/20 0.34
▸ SLC2A2 P11168 1/20 0.34
▸ SLC2A3 P11169 1/20 0.34
▸ CHRM4 P08173 1/20 0.33
▸ PSEN1 P49768 1/20 0.33
▸ PSEN2 P49810 1/20 0.33
▸ APH1B Q8WW43 1/20 0.33
▸ NCSTN Q92542 1/20 0.33
▸ APH1A Q96BI3 1/20 0.33
▸ PSENEN Q9NZ42 1/20 0.33
▸ CNR2 P34972 5/20 0.33
▸ CRHR1 P34998 1/20 0.33
▸ PTGS1 P23219 1/20 0.32
▸ PTGS2 P35354 1/20 0.32
▸ MAP3K12 Q12852 1/20 0.32
▸ CNR1 P21554 1/20 0.32
▸ KCNH2 Q12809 2/20 0.31
▸ TGFBR1 P36897 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25371509 0.90 TGFBR1 (0.33) EBPSLC2A1SLC2A2SLC2A3PSEN1
SCHEMBL25369931 0.88 EBP (0.38) EBPSLC2A1SLC2A2SLC2A3CHRM4
SCHEMBL26065141 0.86 EBP (0.38) EBPSLC2A1SLC2A2SLC2A3PSEN1
SCHEMBL25373929 0.82 CTSK (0.35) EBPCNR2PTGS1PTGS2
SCHEMBL30567055 0.82 CTSK (0.35) EBPCNR2PTGS1PTGS2
SCHEMBL25369016 0.82 CTSK (0.35) EBPCNR2PTGS1PTGS2
SCHEMBL25370615 0.81 EBP (0.37) EBPCHRM4CNR2CNR1KCNH2
SCHEMBL26065137 0.80 NAMPT (0.38) KCNH2
SCHEMBL25373133 0.80 PSEN1 (0.48) EBPPSEN1PSEN2APH1BNCSTN
SCHEMBL30567080 0.80 PSEN1 (0.48) EBPPSEN1PSEN2APH1BNCSTN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250171463-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF BIOGEN MA INC. 2025-05-29 — — US claimed
EP-4482587-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF Biogen MA Inc. (US) 2025-01-01 — — EP claimed
WO-2023164063-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF BIOGEN MA INC. (US) 2023-08-31 — — WO claimed
US-20250171463-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF BIOGEN MA INC. 2025-05-29 — — US disclosed
EP-4482587-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF Biogen MA Inc. (US) 2025-01-01 — — EP disclosed
WO-2023164063-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF BIOGEN MA INC. (US) 2023-08-31 — — WO disclosed
US-20170145012-A1 PURINONES AS UBIQUITIN-SPECIFIC PROTEASE 1 INHIBITORS FORMA THERAPEUTICS, INC. 2017-05-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170145012-A1 PURINONES AS UBIQUITIN-SPECIFIC PROTEASE 1 INHIBITORS USP1, UBA1, UBXN1 EBP 3792/4885SLC2A1 4700/4885SLC2A2 4843/4885
US-20250171463-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF EBPL, EBP, CREBBP EBP 2/4885SLC2A1 2074/4885SLC2A2 2196/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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