Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 2/20 | 0.36 |
| ▸ | ABL1 | P00519 | 2/20 | 0.35 |
| ▸ | BCR | P11274 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | BRS3 | P32247 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.33 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.33 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.33 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25370900 | 0.88 | TRPV4 (0.42) | TRPV4KDM4ECASP3SMN1; SMN2KMT2A | |
| SCHEMBL26065214 | 0.86 | KDM4E (0.41) | TRPV4KDM4ECASP3ABL1BCR | |
| SCHEMBL26066057 | 0.79 | KCNH2 (0.43) | TRPV4KDM4ECASP3ALDH1A1GAA | |
| SCHEMBL26065732 | 0.79 | TRPV4 (0.39) | TRPV4KDM4ECASP3ALDH1A1GAA | |
| SCHEMBL26065205 | 0.78 | SMN1; SMN2 (0.43) | TRPV4KDM4ECASP3ALDH1A1GAA | |
| SCHEMBL26065760 | 0.78 | CNR1 (0.37) | TRPV4KDM4ECASP3ABL1BCR | |
| SCHEMBL26065210 | 0.77 | CTSK (0.44) | KDM4EABL1BCRALDH1A1GAA | |
| SCHEMBL26064898 | 0.76 | MEN1 (0.43) | TRPV4KDM4EALDH1A1GAASMN1; SMN2 | |
| SCHEMBL25370147 | 0.76 | TRPV4 (0.41) | TRPV4KDM4ECASP3SMN1; SMN2BRS3 | |
| SCHEMBL25363280 | 0.74 | SMN1; SMN2 (0.39) | TRPV4KDM4ECASP3ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023164063-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | BIOGEN MA INC. (US) | 2023-08-31 | — | — | WO | disclosed |