Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26065891 | 0.89 | TRPV4 (0.41) | KMT2ATPSAB1MEN1KCNH2TRPV4 | |
| SCHEMBL26066147 | 0.87 | KCNH2 (0.42) | KMT2ATPSAB1MEN1KCNH2POLB | |
| SCHEMBL25369955 | 0.87 | TRPV4 (0.38) | TRPV4 | |
| SCHEMBL26065920 | 0.82 | EBP (0.39) | KMT2ATPSAB1MEN1KCNH2TRPV4 | |
| SCHEMBL26065919 | 0.82 | EBP (0.39) | KMT2ATPSAB1MEN1KCNH2TRPV4 | |
| SCHEMBL26065762 | 0.82 | EBP (0.39) | KMT2ATPSAB1MEN1KCNH2TRPV4 | |
| SCHEMBL26065774 | 0.80 | TLR7 (0.42) | KMT2ATPSAB1MEN1KCNH2TRPV4 | |
| SCHEMBL26065889 | 0.79 | EBP (0.44) | TPSAB1KCNH2TRPV4KDM2B | |
| SCHEMBL26066067 | 0.78 | KCNH2 (0.43) | TPSAB1KCNH2 | |
| SCHEMBL26065535 | 0.78 | MEN1 (0.42) | KMT2AMEN1TRPV4ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023164063-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | BIOGEN MA INC. (US) | 2023-08-31 | — | — | WO | disclosed |