Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | TRPV4 | Q9HBA0 | 6/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | BCR | P11274 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26065759 | 0.94 | KCNH2 (0.36) | KDM4ETRPV4GAALMNAALDH1A1 | |
| SCHEMBL26065910 | 0.90 | LMNA (0.38) | KDM4ETRPV4GAALMNAALDH1A1 | |
| SCHEMBL26065914 | 0.90 | LMNA (0.38) | KDM4ETRPV4GAALMNAALDH1A1 | |
| SCHEMBL26065915 | 0.90 | LMNA (0.38) | KDM4ETRPV4GAALMNAALDH1A1 | |
| SCHEMBL26065897 | 0.88 | KCNH2 (0.41) | KDM4ETRPV4GAALMNAALDH1A1 | |
| SCHEMBL26065896 | 0.88 | KCNH2 (0.41) | KDM4ETRPV4GAALMNAALDH1A1 | |
| SCHEMBL26065890 | 0.88 | KCNH2 (0.41) | KDM4ETRPV4GAALMNAALDH1A1 | |
| SCHEMBL25368924 | 0.88 | TRPV4 (0.37) | TRPV4 | |
| SCHEMBL25368920 | 0.88 | TRPV4 (0.37) | TRPV4 | |
| SCHEMBL25368928 | 0.88 | TRPV4 (0.37) | TRPV4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023164063-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | BIOGEN MA INC. (US) | 2023-08-31 | — | — | WO | disclosed |