Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26065897 | 1.00 | KCNH2 (0.41) | KCNH2CNR1TRPV4LMNAGAA | |
| SCHEMBL26065890 | 1.00 | KCNH2 (0.41) | KCNH2CNR1TRPV4LMNAGAA | |
| SCHEMBL26065759 | 0.94 | KCNH2 (0.36) | KCNH2CNR1TRPV4LMNAGAA | |
| SCHEMBL26065910 | 0.90 | LMNA (0.38) | CNR1TRPV4LMNAGAAKDM4E | |
| SCHEMBL26065915 | 0.90 | LMNA (0.38) | CNR1TRPV4LMNAGAAKDM4E | |
| SCHEMBL26065914 | 0.90 | LMNA (0.38) | CNR1TRPV4LMNAGAAKDM4E | |
| SCHEMBL26065775 | 0.88 | KDM4E (0.36) | KCNH2CNR1TRPV4LMNAGAA | |
| SCHEMBL25370786 | 0.87 | TRPV4 (0.39) | KCNH2CNR1TRPV4SMN1; SMN2PSEN1 | |
| SCHEMBL25370790 | 0.87 | TRPV4 (0.39) | KCNH2CNR1TRPV4SMN1; SMN2PSEN1 | |
| SCHEMBL25372346 | 0.87 | TRPV4 (0.39) | KCNH2CNR1TRPV4SMN1; SMN2PSEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023164063-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | BIOGEN MA INC. (US) | 2023-08-31 | — | — | WO | disclosed |