Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 12/20 | 0.44 |
| ▸ | HTR7 | P34969 | 12/20 | 0.44 |
| ▸ | HTR6 | P50406 | 12/20 | 0.44 |
| ▸ | HTR1A | P08908 | 11/20 | 0.44 |
| ▸ | HTR2A | P28223 | 11/20 | 0.44 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25371215 | 0.86 | TRPV4 (0.43) | DRD2HTR7HTR6HTR1AHTR2A | |
| SCHEMBL30567053 | 0.86 | TRPV4 (0.43) | DRD2HTR7HTR6HTR1AHTR2A | |
| SCHEMBL26065980 | 0.84 | POLB (0.54) | TRPV4MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL26066053 | 0.83 | L3MBTL1 (0.45) | TRPV4MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL26065891 | 0.83 | TRPV4 (0.41) | TRPV4MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL26065889 | 0.83 | EBP (0.44) | TRPV4 | |
| SCHEMBL26065919 | 0.81 | EBP (0.39) | TRPV4MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL26065982 | 0.81 | L3MBTL1 (0.39) | DRD2DRD3TRPV4MEN1KMT2A | |
| SCHEMBL26065920 | 0.81 | EBP (0.39) | TRPV4MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL26065762 | 0.81 | EBP (0.39) | TRPV4MEN1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023164063-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | BIOGEN MA INC. (US) | 2023-08-31 | — | — | WO | disclosed |