Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 8/20 | 0.35 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 7/20 | 0.35 |
| ▸ | HTR2A | P28223 | 6/20 | 0.35 |
| ▸ | HTR7 | P34969 | 5/20 | 0.35 |
| ▸ | HTR6 | P50406 | 5/20 | 0.35 |
| ▸ | DRD4 | P21917 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | BRS3 | P32247 | 3/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | NPY2R | P49146 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25371215 | 1.00 | TRPV4 (0.43) | TRPV4DRD2DRD3HTR1AHTR2A | |
| SCHEMBL26066052 | 0.86 | DRD2 (0.44) | TRPV4DRD2DRD3HTR1AHTR2A | |
| SCHEMBL30567044 | 0.85 | TRPV4 (0.44) | TRPV4BRS3 | |
| SCHEMBL25371906 | 0.85 | TRPV4 (0.44) | TRPV4BRS3 | |
| SCHEMBL25370942 | 0.84 | TRPV4 (0.43) | TRPV4BRS3NR1H2NR1H3NPY2R | |
| SCHEMBL25369108 | 0.84 | TRPV4 (0.39) | TRPV4BRS3 | |
| SCHEMBL30567037 | 0.84 | TRPV4 (0.39) | TRPV4BRS3 | |
| SCHEMBL25369115 | 0.84 | TRPV4 (0.39) | TRPV4BRS3 | |
| SCHEMBL26065597 | 0.84 | TRPV4 (0.41) | TRPV4KCNH2 | |
| SCHEMBL30567051 | 0.83 | TRPV4 (0.39) | TRPV4BRS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4482587-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | Biogen MA Inc. (US) | 2025-01-01 | — | — | EP | claimed |
| WO-2023164063-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | BIOGEN MA INC. (US) | 2023-08-31 | — | — | WO | claimed |
| EP-4482587-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | Biogen MA Inc. (US) | 2025-01-01 | — | — | EP | disclosed |
| WO-2023164063-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | BIOGEN MA INC. (US) | 2023-08-31 | — | — | WO | disclosed |