Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CCR1 | P32246 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25369886 | 0.89 | TRPV4 (0.36) | MEN1KMT2ATRPV4HSD11B1 | |
| SCHEMBL25369892 | 0.89 | TRPV4 (0.36) | MEN1KMT2ATRPV4HSD11B1 | |
| SCHEMBL26066212 | 0.88 | TRPV4 (0.43) | MEN1KMT2ASMN1; SMN2TRPV4HSD11B1 | |
| SCHEMBL26066093 | 0.84 | MEN1 (0.41) | MEN1KMT2ASMN1; SMN2TRPV4HSD11B1 | |
| SCHEMBL26065887 | 0.79 | MEN1 (0.42) | MEN1KMT2ASMN1; SMN2TRPV4KDM4E | |
| SCHEMBL26065680 | 0.79 | GCK (0.37) | MEN1KMT2ASMN1; SMN2TRPV4HSD11B1 | |
| SCHEMBL26066081 | 0.77 | MAPT (0.43) | MEN1KMT2ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL25369944 | 0.77 | TRPV4 (0.44) | MEN1KMT2ATRPV4HSD11B1KDM4E | |
| SCHEMBL25369939 | 0.77 | TRPV4 (0.44) | MEN1KMT2ATRPV4HSD11B1KDM4E | |
| SCHEMBL30567026 | 0.77 | TRPV4 (0.44) | MEN1KMT2ATRPV4HSD11B1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023164063-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | BIOGEN MA INC. (US) | 2023-08-31 | — | — | WO | disclosed |