Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | IKBKB | O14920 | 2/20 | 0.40 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.40 |
| ▸ | PRKCG | P05129 | 2/20 | 0.40 |
| ▸ | PRKCB | P05771 | 2/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | PRKCA | P17252 | 2/20 | 0.40 |
| ▸ | PRKACA | P17612 | 2/20 | 0.40 |
| ▸ | PRKACG | P22612 | 2/20 | 0.40 |
| ▸ | PRKACB | P22694 | 2/20 | 0.40 |
| ▸ | PRKCH | P24723 | 2/20 | 0.40 |
| ▸ | PRKCI | P41743 | 2/20 | 0.40 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.40 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.40 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.40 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.40 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26065566 | 0.82 | MAPT (0.47) | MAPTPKMCYP3A4IKBKBPRKD3 | |
| SCHEMBL26065736 | 0.81 | ALDH1A1 (0.48) | MAPTPKMCYP3A4IKBKBPRKD3 | |
| SCHEMBL26065642 | 0.80 | CYP3A4 (0.40) | MAPTPKMCYP3A4PRKD3PRKCG | |
| SCHEMBL26066093 | 0.79 | MEN1 (0.41) | KDM4EALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL26066147 | 0.78 | KCNH2 (0.42) | KDM4EALDH1A1KMT2AMEN1HTR1A | |
| SCHEMBL26066077 | 0.78 | TGM2 (0.49) | — | |
| Trifluoroacetic Acid SCHEMBL25371821 | 0.77 | TRPV4 (0.35) | NR1I2BRS3 | |
| SCHEMBL26066067 | 0.77 | KCNH2 (0.43) | KCNH2 | |
| SCHEMBL26066097 | 0.77 | MEN1 (0.40) | KDM4EALDH1A1KMT2ALMNAMEN1 | |
| SCHEMBL25369101 | 0.76 | TRPV1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023164063-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | BIOGEN MA INC. (US) | 2023-08-31 | — | — | WO | disclosed |