Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 1/20 | 0.37 |
| ▸ | CCR1 | P32246 | 3/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 4/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 4/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 4/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 4/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 4/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25370833 | 0.89 | PSEN1 (0.34) | CCR1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL30567047 | 0.89 | PSEN1 (0.34) | CCR1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL26065730 | 0.86 | CCR1 (0.36) | CCR1MEN1KMT2ATRPV4ALOX5AP | |
| SCHEMBL26066097 | 0.79 | MEN1 (0.40) | CCR1MEN1KMT2ASMN1; SMN2TRPV4 | |
| SCHEMBL26065673 | 0.77 | PSEN1 (0.40) | CHRM5CYP17A1PSEN1PSEN2APH1B | |
| SCHEMBL26065669 | 0.77 | TGM2 (0.48) | — | |
| SCHEMBL26066212 | 0.76 | TRPV4 (0.43) | CCR1MEN1KMT2ASMN1; SMN2TRPV4 | |
| SCHEMBL25372096 | 0.76 | TRPV4 (0.35) | CCR1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL25370537 | 0.76 | TRPV4 (0.35) | CCR1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL25370535 | 0.76 | TRPV4 (0.35) | CCR1PSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023164063-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | BIOGEN MA INC. (US) | 2023-08-31 | — | — | WO | disclosed |