SCHEMBL260676

SCHEMBL260676

CC(O)Cn1c(=O)n(CC(C)O)c(=O)n(CC(C)O)c1=O

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.43
MAPK1 P28482 2/20 0.41
ALDH1A1 P00352 2/20 0.41
MAPT P10636 1/20 0.41
ATM Q13315 1/20 0.39
LMNA P02545 2/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
CSNK2A1 P68400 3/20 0.35
RAB9A P51151 1/20 0.34
RGS4 P49798 2/20 0.33
TSHR P16473 2/20 0.33
RGS8 P57771 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
ADORA2A P29274 1/20 0.33
ADORA2B P29275 1/20 0.33
ADORA1 P30542 1/20 0.33
PTGS1 P23219 1/20 0.32
PTGS2 P35354 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11690456 0.91 KDM4E (0.39) KDM4EMAPK1ALDH1A1MAPTATM
SCHEMBL14283656 0.89 KDM4E (0.38) KDM4EMAPK1ALDH1A1MAPTATM
SCHEMBL10711246 0.87 KDM4E (0.40) KDM4EMAPK1ALDH1A1MAPTATM
SCHEMBL10951033 0.84 APEX1 (0.44) KDM4EMAPK1ALDH1A1MAPTATM
SCHEMBL13847007 0.83 RAB9A (0.36) KDM4EMAPK1ALDH1A1MAPTATM
SCHEMBL7160182 0.83 CYP3A4 (0.61) KDM4EMAPK1ALDH1A1MAPTATM
SCHEMBL7162162 0.83 CYP3A4 (0.61) KDM4EMAPK1ALDH1A1MAPTATM
SCHEMBL15015029 0.80 TP53 (0.64) KDM4EMAPK1ALDH1A1MAPTATM
SCHEMBL11689200 0.80 MAPK1 (0.37) KDM4EMAPK1ALDH1A1MAPTATM
SCHEMBL11598806 0.80 AGER (0.53) KDM4EALDH1A1SMN1; SMN2RAB9APTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 200 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119161379-A Intumescent nitrogen-phosphorus flame retardant and preparation method thereof 南京林业大学 2024-12-20 CN claimed
EP-2414424-B1 THERMOSETTING COMPOSITIONS CONTAINING ISOCYANURATE RINGS POLYNT COMPOSITES USA INC (US) 2018-12-19 EP claimed
US-8758888-B2 Crosslinkable imide polyester coating VALSPAR SOURCING, INC. (US) 2014-06-24 US claimed
US-8501877-B2 Thermosetting compositions containing isocyanurate rings CCP COMPOSITES US LLC (US) 2013-08-06 US claimed
EP-2142367-B1 CROSSLINKABLE IMIDE POLYESTER COATING VALSPAR SOURCING INC (US) 2013-06-26 EP claimed
EP-2414424-A1 THERMOSETTING COMPOSITIONS CONTAINING ISOCYANURATE RINGS Cook Composites and Polymers Company (US) 2012-02-08 EP claimed
US-20100256285-A1 Thermosetting Compositions Containing Isocyanurate Rings Polynt Composites USA Inc. (NL) 2010-10-07 US claimed
WO-2010112179-A1 THERMOSETTING COMPOSITIONS CONTAINING ISOCYANURATE RINGS COOK COMPOSITES AND POLYMERS COMPANY (US) 2010-10-07 WO claimed
US-20100136333-A1 CROSSLINKABLE IMIDE POLYESTER COATING VALSPAR SOURCING, INC. (US) 2010-06-03 US claimed
EP-2142367-A1 CROSSLINKABLE IMIDE POLYESTER COATING Valspar Sourcing, Inc. (US) 2010-01-13 EP claimed
WO-2001072866-A1 POLYURETHANE PREPARED FROM SORBITOL-BRANCHED POLYESTERS CROMPTON CORPORATION (US) 2001-10-04 WO claimed
EP-0242925-B1 COLD-ROLLING OILS FOR STEEL PLATES The Nisshin Oil Mills, Ltd. (JP) 1990-11-22 EP claimed
EP-0242925-A2 Cold-rolling oils for steel plates The Nisshin Oil Mills, Ltd. (JP) 1987-10-28 EP claimed
EP-0003620-B1 PREPARATION OF TRIS-(BETA-HYDROXYPROPYL) ISOCYANURATE STAMICARBON B.V. (NL) 1984-06-06 EP claimed
EP-0004116-B1 PROCESS FOR THE PREPARATION OF CROSS-LINKED POLYURETHANES STAMICARBON B.V. (NL) 1983-02-16 EP claimed
US-4245080-A AND A POLYETHER, DIOL, AND DIISOCYANATE STAMICARBON, B.V. (NL) 1981-01-13 US claimed
US-4235977-A Cross-linked polyurethane elastomers and microcellular foams STAMICARBON, B.V. (NL) 1980-11-25 US claimed
US-4198505-A Preparation of tris-(β-hydroxypropyl) isocyanurate STAMICARBON, B.V. (NL) 1980-04-15 US claimed
EP-0004116-A1 Process for the preparation of cross-linked polyurethanes STAMICARBON B.V. (NL) 1979-09-19 EP claimed
EP-0003620-A1 Preparation of tris-(beta-hydroxypropyl) isocyanurate STAMICARBON B.V. (NL) 1979-08-22 EP claimed