SCHEMBL26067689

SCHEMBL26067689

COCCO[C@H]1C(O)[C@@H](COP(=O)(O)OC2[C@@H](COP(=O)(O)O)O[C@@H](n3cnc4c(N)ncnc43)[C@H]2OCCOC)O[C@H]1n1cnc2c(=O)[nH]c(N)nc21

nearest known ligand 0.67

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ RNASEL Q05823 13/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26067688 0.97 RNASEL (0.69) RNASEL
SCHEMBL25401787 0.97 RNASEL (0.69) RNASEL
SCHEMBL26067588 0.95 RNASEL (0.59) RNASEL
SCHEMBL26067572 0.95 RNASEL (0.59) RNASEL
SCHEMBL26067571 0.92 RNASEL (0.62) RNASEL
SCHEMBL26067587 0.92 RNASEL (0.62) RNASEL
SCHEMBL27062506 0.91 RNASEL (0.55) RNASEL
SCHEMBL26210432 0.91 RNASEL (0.70) RNASEL
SCHEMBL24170753 0.91 RNASEL (0.72) RNASEL
SCHEMBL24162835 0.91 RNASEL (0.72) RNASEL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230250127-A1 MODIFIED mRNA 5'-CAP ANALOGS Nanjing GeneLeap Biotechnology Co., Ltd. (CN) 2023-08-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230250127-A1 MODIFIED mRNA 5'-CAP ANALOGS RNGTT, RNMT, NSUN2 RNASEL 96/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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