SCHEMBL260683

SCHEMBL260683

O=C(c1ccc[nH]1)C(Cl)(Cl)Cl

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.50
TSHR P16473 1/20 0.46
HPGD P15428 2/20 0.45
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
RAB9A P51151 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
ATM Q13315 1/20 0.43
NPC1 O15118 1/20 0.43
HSD17B10 Q99714 1/20 0.43
MAPT P10636 2/20 0.41
CYP1A1 P04798 2/20 0.41
CYP1A2 P05177 2/20 0.41
CYP2D6 P10635 2/20 0.41
CYP1B1 Q16678 2/20 0.41
LMNA P02545 1/20 0.41
AHR P35869 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
POLB P06746 2/20 0.40
RECQL P46063 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27518917 0.82 TSHR (0.48) TSHRMEN1KMT2ARAB9ASMN1; SMN2
SCHEMBL10939118 0.81 ALDH1A1 (0.43) ALDH1A1TSHRHPGDMEN1KMT2A
SCHEMBL14437869 0.79 TSHR (0.43) TSHRMEN1KMT2ARAB9ASMN1; SMN2
SCHEMBL1656536 0.78 MAOB (0.46) TSHRMEN1KMT2ARAB9ASMN1; SMN2
SCHEMBL3181190 0.78 TSHR (0.46) TSHRRAB9ASMN1; SMN2ATMNPC1
SCHEMBL8885937 0.75 MAOB (0.44) TSHRMEN1KMT2ARAB9ASMN1; SMN2
SCHEMBL27916020 0.75
SCHEMBL591099 0.75
SCHEMBL18414897 0.74 TSHR (0.37) TSHRMEN1KMT2ARAB9ASMN1; SMN2
SCHEMBL371069 0.74 TSHR (0.54) TSHRMEN1KMT2ARAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 597 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117427693-B Preparation method of catalyst for synthesizing 2,3, 6-trimethylphenol from m-cresol 安徽海华科技集团有限公司 2025-05-06 CN claimed
CN-116655515-B N-alkoxy-1-acyl-1H-pyrrole-2-amide compound and application thereof 中山大学 2024-05-03 CN claimed
CN-117427693-A Preparation method of catalyst for synthesizing 2,3, 6-trimethylphenol from m-cresol 安徽海华科技集团有限公司 2024-01-23 CN claimed
CN-115448909-B N-carbazolyl-1H-pyrrole-2-carboxamide and application thereof as ligand in copper-catalyzed C-N coupling reaction 中山大学 2023-10-27 CN claimed
CN-116655515-A N-alkoxy-1-acyl-1H-pyrrole-2-amide compound and application thereof 中山大学 2023-08-29 CN claimed
CN-114456099-A Preparation method of 4-chloropyrrole-2-carboxylic acid 八叶草健康产业研究院(厦门)有限公司 2022-05-10 CN claimed
EP-2016047-B1 BIPHENYL AMIDE LACTAM DERIVATIVES AS INHIBITORS OF 11- BETA-HYDROXYSTEROID DEHYDROGENASE 1 LILLY CO ELI (US) 2013-08-28 EP claimed
EP-0693072-B9 METHOD FOR THE SYNTHESIS OF 4- AND/OR 5-(DI)SUBSTITUTED 2-AMINOIMIDAZOLES FROM 2-AMINOIMIDAZOLES AND ALDEHYDES UNIV COLUMBIA (US) 2004-09-15 EP claimed
EP-0693072-B1 METHOD FOR THE SYNTHESIS OF 4- AND/OR 5-(DI)SUBSTITUTED 2-AMINOIMIDAZOLES FROM 2-AMINOIMIDAZOLES AND ALDEHYDES UNIV COLUMBIA (US) 2003-12-03 EP claimed
EP-0693072-A4 METHOD FOR THE SYNTHESIS OF 4- AND/OR 5-(DI)SUBSTITUTED 2-AMINOIMIDAZOLES FROM 2-AMINOIMIDAZOLES AND ALDEHYDES UNIV COLUMBIA (US) 1997-09-24 EP claimed
EP-0693072-A1 METHOD FOR THE SYNTHESIS OF 4- AND/OR 5-(DI)SUBSTITUTED 2-AMINOIMIDAZOLES FROM 2-AMINOIMIDAZOLES AND ALDEHYDES The Trustees of Columbia University in the City of New York (US) 1996-01-24 EP claimed
WO-1994024136-A1 METHOD FOR THE SYNTHESIS OF 4- AND/OR 5-(DI)SUBSTITUTED 2-AMINOIMIDAZOLES FROM 2-AMINOIMIDAZOLES AND ALDEHYDES THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 1994-10-27 WO claimed
US-12570612-B2 Substituted nitrogen heterocyclic compound and anesthetic effect thereof CHENGDU MFS PHARMA. CO., LTD. (CN) 2026-03-10 US disclosed
US-20260062443-A1 PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS ALEXION PHARMA INC (US) 2026-03-05 US disclosed
EP-4655069-A1 PYRIDAZINES AS SARM1 INHIBITORS Disarm Therapeutics, Inc. (US) 2025-12-03 EP disclosed
US-20250313546-A1 NUCLEIC ACID BINDERS UNIVERSITY OF STRATHCLYDE (GB) 2025-10-09 US disclosed
US-4046775-A 4,5-Dihalopyrrole-2-carboxamides STERLING DRUG INC. (US) 1977-09-06 US disclosed
US-4000160-A BACTERICIDES, FUNGICIDES STERLING DRUG INC. (US) 1976-12-28 US disclosed
US-3963480-A Herbicidal pyrrole-2-carboxamides STERLING DRUG INC. (US) 1976-06-15 US disclosed
US-3963746-A ANTIBACTERIAL, HERBICIDE, INSECTICIDE STERLING DRUG INC. (US) 1976-06-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260062443-A1 PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS C9, SSB, C1S ALDH1A1 3835/4885TSHR 1164/4885HPGD 4023/4885
US-12570612-B2 Substituted nitrogen heterocyclic compound and anesthetic effect thereof CNR1, SCN8A, KCNH1 ALDH1A1 1090/4885TSHR 565/4885HPGD 1012/4885
US-20250313546-A1 NUCLEIC ACID BINDERS ZFR, NSUN3, POLI ALDH1A1 3362/4885TSHR 3988/4885HPGD 4572/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.