Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 1/20 | 0.47 |
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | CDK4 | P11802 | 4/20 | 0.42 |
| ▸ | CCND1 | P24385 | 4/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | ASH1L | Q9NR48 | 2/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.36 |
| ▸ | ESRRG | P62508 | 2/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | ACLY | P53396 | 2/20 | 0.35 |
| ▸ | BCL2 | P10415 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7926785 | 0.82 | ESR1 (0.38) | PLGPLAUCYP19A1KDM4EMEN1 | |
| SCHEMBL14274534 | 0.81 | PLG (0.49) | PLGPLAUCDK4CCND1CYP19A1 | |
| SCHEMBL30364970 | 0.79 | PLAU (0.48) | PLGPLAUCDK4CCND1ASH1L | |
| SCHEMBL23902750 | 0.79 | PLAU (0.48) | PLGPLAUCDK4CCND1ASH1L | |
| SCHEMBL3919143 | 0.78 | MEN1 (0.54) | PLGPLAUCDK4CCND1CYP19A1 | |
| SCHEMBL21245279 | 0.78 | PLG (0.54) | PLGPLAUCDK4CCND1CYP19A1 | |
| SCHEMBL15770690 | 0.78 | CYP19A1 (0.41) | PLGPLAUCDK4CCND1CYP19A1 | |
| SCHEMBL13281578 | 0.77 | MCL1 (0.47) | MCL1BCL2 | |
| SCHEMBL27587769 | 0.77 | ALOX5 (0.50) | PLGPLAUCDK4CCND1MCL1 | |
| SCHEMBL21051475 | 0.73 | GLO1 (0.50) | PLGPLAUCYP19A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219477-A1 | CYANOTRIAZOLE COMPOUNDS | Otsuka Pharmaceutical Co., Ltd. (JP) | 2023-08-02 | — | — | EP | disclosed |