Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | KMO | O15229 | 1/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.46 |
| ▸ | PLG | P00747 | 1/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.45 |
| ▸ | ESRRG | P62508 | 2/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGAV | P06756 | 1/20 | 0.42 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.42 |
| ▸ | ACLY | P53396 | 2/20 | 0.41 |
| ▸ | CDK4 | P11802 | 2/20 | 0.41 |
| ▸ | CCND1 | P24385 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL416378 | 0.84 | ALOX5 (0.49) | ALOX5EPHX2KMOFFAR4MCL1 | |
| SCHEMBL416786 | 0.84 | KMO (0.65) | ALOX5EPHX2KMOFFAR4MCL1 | |
| SCHEMBL418370 | 0.84 | P2RX7 (0.50) | ALOX5EPHX2KMOFFAR4MCL1 | |
| SCHEMBL4466329 | 0.81 | TNF (0.60) | ALOX5EPHX2MCL1 | |
| SCHEMBL4234811 | 0.81 | KMT2A (0.62) | ITGB3 | |
| SCHEMBL30103437 | 0.81 | KMT2A (0.62) | ITGB3 | |
| SCHEMBL413159 | 0.80 | FFAR4 (0.55) | ALOX5EPHX2KMOFFAR4MCL1 | |
| SCHEMBL14274534 | 0.80 | PLG (0.49) | MCL1PLGPLAUESRRGCDK4 | |
| SCHEMBL1967792 | 0.80 | CDK4 (0.68) | KMOCDK4CCND1 | |
| SCHEMBL29560163 | 0.80 | CDK4 (0.68) | KMOCDK4CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1558897-A | oral antidiabetic agent | ����-�����ع�˾ | 2004-12-29 | — | — | CN | disclosed |