Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | METAP2 | P50579 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | RXRG | P48443 | 1/20 | 0.32 |
| ▸ | IKBKB | O14920 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18004000 | 0.84 | CTSS (0.43) | CTSKCTSSXDHCYP1A2METAP2 | |
| SCHEMBL18004266 | 0.83 | CTSS (0.36) | CTSKCTSSXDHCYP1A2METAP2 | |
| SCHEMBL16399113 | 0.83 | CTSS (0.36) | CTSKCTSSXDHCYP1A2METAP2 | |
| SCHEMBL18003964 | 0.80 | RXRA (0.41) | CTSKCTSSXDHRXRARXRG | |
| SCHEMBL16399375 | 0.78 | CTSS (0.34) | CTSKCTSSXDHCYP1A2METAP2 | |
| SCHEMBL18004377 | 0.77 | CTSS (0.38) | CTSKCTSSXDHCYP1A2METAP2 | |
| SCHEMBL26070319 | 0.77 | CTSS (0.35) | CTSKCTSSCYP1A2METAP2IKBKB | |
| SCHEMBL18003856 | 0.77 | CTSS (0.38) | CTSKCTSSXDHCYP1A2METAP2 | |
| SCHEMBL18003491 | 0.77 | CTSS (0.36) | CTSKCTSSXDHCYP1A2METAP2 | |
| SCHEMBL18004505 | 0.76 | CTSS (0.37) | CTSKCTSSXDHCYP1A2METAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219477-A1 | CYANOTRIAZOLE COMPOUNDS | Otsuka Pharmaceutical Co., Ltd. (JP) | 2023-08-02 | — | — | EP | disclosed |