Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | METAP2 | P50579 | 2/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.32 |
| ▸ | IKBKB | O14920 | 1/20 | 0.31 |
| ▸ | SHMT1 | P34896 | 2/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.31 |
| ▸ | DHODH | Q02127 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18003747 | 0.85 | CTSS (0.33) | CTSSCTSKCYP1A2METAP2 | |
| SCHEMBL18004000 | 0.80 | CTSS (0.43) | CTSSCTSKCYP1A2METAP2IKBKB | |
| SCHEMBL18004266 | 0.79 | CTSS (0.36) | CTSSCTSKCYP1A2METAP2PTGDR2 | |
| SCHEMBL18004215 | 0.77 | NOTUM (0.41) | CTSSCTSKCYP1A2METAP2IKBKB | |
| SCHEMBL26070294 | 0.77 | CTSK (0.37) | CTSSCTSKCYP1A2METAP2IKBKB | |
| SCHEMBL18003772 | 0.77 | AR (0.35) | CTSSCTSKCYP1A2METAP2PTGDR2 | |
| SCHEMBL16399113 | 0.76 | CTSS (0.36) | CTSSCTSKCYP1A2METAP2IKBKB | |
| SCHEMBL18005549 | 0.76 | KDM4E (0.31) | CTSSCTSK | |
| SCHEMBL26070221 | 0.76 | DAO (0.30) | — | |
| SCHEMBL18003856 | 0.76 | CTSS (0.38) | CTSSCTSKCYP1A2METAP2IKBKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219477-A1 | CYANOTRIAZOLE COMPOUNDS | Otsuka Pharmaceutical Co., Ltd. (JP) | 2023-08-02 | — | — | EP | disclosed |