Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | SCN4A | P35499 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | HAO1 | Q9UJM8 | 2/20 | 0.34 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21945135 | 0.84 | ADORA2A (0.42) | MAPTLMNAALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL21945114 | 0.82 | MEN1 (0.39) | MAPTLMNAHAO1MEN1ALDH1A1 | |
| SCHEMBL21945093 | 0.81 | ADORA2A (0.41) | SCN9AMAPTLMNAALDH1A1CYP1A2 | |
| SCHEMBL21945732 | 0.79 | MAOA (0.38) | SCN4AMAPTLMNAMAOBBTK | |
| SCHEMBL21945192 | 0.78 | MAPT (0.37) | SCN9AMAPTLMNA | |
| SCHEMBL21945763 | 0.77 | DRD1 (0.40) | SCN9AMAPTALDH1A1MGLL | |
| SCHEMBL21945053 | 0.77 | NMT1 (0.36) | MAPTMAOBMEN1ALOX15NFKB1 | |
| SCHEMBL21945696 | 0.76 | NPSR1 (0.35) | SCN4ASCN9AMAPTLMNACYP1A2 | |
| SCHEMBL21945229 | 0.75 | LTA4H (0.39) | HAO1MAOBCYP2D6CYP2C9NPSR1 | |
| SCHEMBL26070235 | 0.75 | HTR2A (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219477-A1 | CYANOTRIAZOLE COMPOUNDS | Otsuka Pharmaceutical Co., Ltd. (JP) | 2023-08-02 | — | — | EP | disclosed |