Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | TTBK1 | Q5TCY1 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21945135 | 0.92 | ADORA2A (0.42) | ADORA2AKIF11BTKSMN1; SMN2CYP2C9 | |
| SCHEMBL21945754 | 0.86 | KIF11 (0.38) | ADORA2AKIF11BTKSMN1; SMN2CYP2C9 | |
| SCHEMBL21945228 | 0.86 | EGFR (0.40) | ADORA2ACYP2C9CYP2C19L3MBTL1NPSR1 | |
| SCHEMBL21945696 | 0.85 | NPSR1 (0.35) | ADORA2ABTKSMN1; SMN2CYP2C9CYP2C19 | |
| SCHEMBL21945096 | 0.83 | AR (0.34) | ADORA2AKIF11CYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL21945706 | 0.81 | ADORA2A (0.34) | ADORA2AKIF11SMN1; SMN2CYP2C9CYP2C19 | |
| SCHEMBL26070656 | 0.81 | DHODH (0.38) | BTKCYP2C9CYP2C19NPSR1CYP1A2 | |
| SCHEMBL21945094 | 0.81 | TLR8 (0.34) | MAPTLTA4HALDH1A1KDM4ELMNA | |
| SCHEMBL21945229 | 0.78 | LTA4H (0.39) | CYP2C9NPSR1LTA4H | |
| SCHEMBL21945164 | 0.77 | MAOB (0.42) | CYP1A2CYP3A4ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10626095-B2 | Cyanotriazole compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2020-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10626095-B2 | Cyanotriazole compounds | CS, PC, ACAT1 | ADORA2A 3683/4885KIF11 3245/4885CHEK2 747/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.