Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | IGF1R | P08069 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | DHFR | P00374 | 4/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.38 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.37 |
| ▸ | SLC9A3 | P48764 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26071070 | 0.89 | SMN1; SMN2 (0.45) | LMNAMAPK1HTTSMN1; SMN2DHFR | |
| SCHEMBL18006355 | 0.84 | MAOB (0.39) | SIRT2MAOBLMNAMAPK1HTT | |
| SCHEMBL26070995 | 0.84 | KDM4E (0.42) | SIRT2MAOBIGF1RSMN1; SMN2TAAR1 | |
| SCHEMBL26070928 | 0.81 | KDM4E (0.37) | BACE1SMN1; SMN2TAAR1GP6KDM4E | |
| SCHEMBL26070926 | 0.77 | TTK (0.52) | LMNAMAPK1SMN1; SMN2TAAR1KDM4E | |
| SCHEMBL26070999 | 0.77 | SIRT2 (0.43) | SIRT2MAOBIGF1RSMN1; SMN2TAAR1 | |
| SCHEMBL26071072 | 0.76 | SLC22A12 (0.40) | IGF1RBACE1HTR6DHFR | |
| SCHEMBL26070997 | 0.75 | KDM4E (0.40) | IGF1RSMN1; SMN2DHFRKDM4E | |
| SCHEMBL26071027 | 0.75 | SIRT2 (0.39) | SIRT2MAOBBACE1LMNASMN1; SMN2 | |
| SCHEMBL18004881 | 0.74 | GPR84 (0.39) | SIRT2MAOBBACE1GP6KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219477-A1 | CYANOTRIAZOLE COMPOUNDS | Otsuka Pharmaceutical Co., Ltd. (JP) | 2023-08-02 | — | — | EP | disclosed |