Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 5/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26070912 | 0.89 | IGF1R (0.45) | IGF1RMEN1KMT2AMAPTKDM4E | |
| SCHEMBL18006329 | 0.86 | PDE4B (0.41) | CYP3A4CYP2D6CYP2C9CYP1A2HRH3 | |
| SCHEMBL26070984 | 0.80 | IGF1R (0.42) | IGF1RMEN1KMT2AMAPTKDM4E | |
| SCHEMBL26071029 | 0.77 | FFAR1 (0.39) | IGF1RTSHRLMNA | |
| SCHEMBL18006274 | 0.77 | CYP2D6 (0.45) | CYP3A4CYP2D6CYP2C9CYP1A2HRH3 | |
| SCHEMBL26070965 | 0.76 | IGF1R (0.42) | IGF1RSIRT2SIRT1SIRT3LMNA | |
| SCHEMBL26071031 | 0.75 | PIK3CD (0.39) | IGF1RMEN1KMT2ALMNAMAPT | |
| SCHEMBL26070969 | 0.75 | TAAR1 (0.43) | IGF1RSIRT1MEN1TSHRKMT2A | |
| SCHEMBL26071092 | 0.75 | IGF1R (0.39) | IGF1RMEN1KMT2AMAPTKDM4E | |
| SCHEMBL18006330 | 0.74 | NAAA (0.40) | IGF1RMEN1KMT2AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219477-A1 | CYANOTRIAZOLE COMPOUNDS | Otsuka Pharmaceutical Co., Ltd. (JP) | 2023-08-02 | — | — | EP | disclosed |