Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 9/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MPO | P05164 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.37 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.37 |
| ▸ | TBK1 | Q9UHD2 | 2/20 | 0.37 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.37 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.37 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | PRKDC | P78527 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.36 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18006362 | 0.86 | LMNA (0.37) | IGF1RLMNAMPOSIRT2SIRT1 | |
| SCHEMBL26070912 | 0.78 | IGF1R (0.45) | IGF1RPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL26070909 | 0.76 | IGF1R (0.42) | IGF1RLMNASIRT2SIRT1SIRT3 | |
| SCHEMBL26071035 | 0.76 | CYP4F2 (0.46) | — | |
| SCHEMBL26070984 | 0.76 | IGF1R (0.42) | IGF1RPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL26071088 | 0.74 | ADORA2A (0.42) | IGF1RMPOPIK3CDPIK3CAPIK3CB | |
| SCHEMBL26070961 | 0.74 | MEN1 (0.42) | IGF1R | |
| SCHEMBL26070980 | 0.73 | NOS1 (0.48) | — | |
| SCHEMBL26071092 | 0.72 | IGF1R (0.39) | IGF1RPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL26071059 | 0.72 | PFKFB3 (0.39) | IGF1RMPOPIK3CDPIK3CAPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219477-A1 | CYANOTRIAZOLE COMPOUNDS | Otsuka Pharmaceutical Co., Ltd. (JP) | 2023-08-02 | — | — | EP | disclosed |