Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.39 |
| ▸ | PARP1 | P09874 | 3/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CCNC | P24863 | 1/20 | 0.37 |
| ▸ | CDK8 | P49336 | 1/20 | 0.37 |
| ▸ | IGF1R | P08069 | 5/20 | 0.37 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18006405 | 0.88 | NAAA (0.38) | FFAR1FFAR4PARP1DDB1CRBN | |
| SCHEMBL26070912 | 0.81 | IGF1R (0.45) | IGF1R | |
| SCHEMBL26070944 | 0.79 | POLB (0.54) | — | |
| SCHEMBL18006310 | 0.79 | MAOA (0.38) | FFAR1FFAR4PARP1LMNAHTT | |
| SCHEMBL26070946 | 0.78 | POLB (0.48) | FFAR1LMNA | |
| SCHEMBL26070909 | 0.77 | IGF1R (0.42) | LMNAIGF1RTSHR | |
| SCHEMBL26070984 | 0.76 | IGF1R (0.42) | IGF1R | |
| SCHEMBL26071031 | 0.74 | PIK3CD (0.39) | LMNASMN1; SMN2IGF1RF10 | |
| SCHEMBL26070969 | 0.74 | TAAR1 (0.43) | SMN1; SMN2IGF1RTSHR | |
| SCHEMBL26071092 | 0.73 | IGF1R (0.39) | IGF1RF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219477-A1 | CYANOTRIAZOLE COMPOUNDS | Otsuka Pharmaceutical Co., Ltd. (JP) | 2023-08-02 | — | — | EP | disclosed |