Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.35 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.34 |
| ▸ | TTK | P33981 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | F9 | P00740 | 1/20 | 0.34 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.33 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | GRK2 | P25098 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18006339 | 0.85 | HPGD (0.35) | KDM4ESMN1; SMN2HPGDLNPEPGP6 | |
| SCHEMBL26070995 | 0.83 | KDM4E (0.42) | KDM4ESMN1; SMN2GP6F9TAAR1 | |
| SCHEMBL26070926 | 0.81 | TTK (0.52) | KDM4ESMN1; SMN2HPGDTTKNOTUM | |
| SCHEMBL26070951 | 0.81 | SIRT2 (0.42) | KDM4ESMN1; SMN2GP6TAAR1BACE1 | |
| SCHEMBL26070999 | 0.76 | SIRT2 (0.43) | KDM4ESMN1; SMN2GP6F9TAAR1 | |
| SCHEMBL26071070 | 0.76 | SMN1; SMN2 (0.45) | KDM4ESMN1; SMN2TAAR1ROCK2GRK2 | |
| SCHEMBL26071075 | 0.75 | CYSLTR2 (0.36) | KDM4ESMN1; SMN2HPGDNOTUM | |
| SCHEMBL26070997 | 0.74 | KDM4E (0.40) | KDM4ESMN1; SMN2NOTUMFGFR2FGFR3 | |
| SCHEMBL26071027 | 0.74 | SIRT2 (0.39) | KDM4ESMN1; SMN2HPGDBACE1ADORA2A | |
| SCHEMBL18006341 | 0.73 | PARP15 (0.40) | PARP15PARP10PARP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219477-A1 | CYANOTRIAZOLE COMPOUNDS | Otsuka Pharmaceutical Co., Ltd. (JP) | 2023-08-02 | — | — | EP | disclosed |