Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 2/20 | 0.35 |
| ▸ | AGXT | P21549 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18006404 | 0.85 | DAO (0.38) | SIRT2SMN1; SMN2KDM4ENPC1HPGD | |
| SCHEMBL26070995 | 0.83 | KDM4E (0.42) | SIRT2SMN1; SMN2KDM4EMAOBMAOA | |
| SCHEMBL26071038 | 0.75 | NR1H2 (0.41) | KDM4E | |
| SCHEMBL26070951 | 0.75 | SIRT2 (0.42) | SIRT2SMN1; SMN2KDM4EMAOBLMNA | |
| SCHEMBL26070926 | 0.75 | TTK (0.52) | SMN1; SMN2KDM4EHPGDTDP1LMNA | |
| SCHEMBL26070999 | 0.75 | SIRT2 (0.43) | SIRT2SMN1; SMN2KDM4ENPC1RAB9A | |
| SCHEMBL26071070 | 0.75 | SMN1; SMN2 (0.45) | SMN1; SMN2KDM4ETDP1LMNA | |
| SCHEMBL26070921 | 0.74 | LMNA (0.38) | MAOBLMNAPKMHSD17B10ADORA2A | |
| SCHEMBL26070928 | 0.74 | KDM4E (0.37) | SMN1; SMN2KDM4EHPGDADORA2AADORA1 | |
| SCHEMBL26070997 | 0.73 | KDM4E (0.40) | SMN1; SMN2KDM4ENPC1RAB9ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219477-A1 | CYANOTRIAZOLE COMPOUNDS | Otsuka Pharmaceutical Co., Ltd. (JP) | 2023-08-02 | — | — | EP | disclosed |