Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | PDK2 | Q15119 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | GAK | O14976 | 1/20 | 0.40 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | NQO2 | P16083 | 1/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.40 |
| ▸ | FECH | P22830 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | TYK2 | P29597 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.40 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.40 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26070946 | 0.95 | POLB (0.48) | POLBPDK2MEN1KMT2ANPC1 | |
| SCHEMBL18006351 | 0.86 | POLB (0.55) | POLBPDK2MEN1KMT2ANPC1 | |
| SCHEMBL18006352 | 0.81 | POLB (0.49) | POLBPDK2NPC1GAKDYRK3 | |
| SCHEMBL26071029 | 0.79 | FFAR1 (0.39) | — | |
| SCHEMBL2227579 | 0.78 | POLB (0.69) | POLBPDK2MEN1KMT2ANPC1 | |
| SCHEMBL5381833 | 0.74 | CLK2 (0.75) | POLBPDK2MEN1KMT2AGAK | |
| SCHEMBL26070907 | 0.73 | NFE2L2 (0.47) | — | |
| SCHEMBL26071070 | 0.73 | SMN1; SMN2 (0.45) | MEN1KMT2A | |
| SCHEMBL15075237 | 0.73 | POLB (0.69) | POLBPDK2MEN1KMT2ANPC1 | |
| SCHEMBL13096997 | 0.73 | POLB (0.73) | POLBPDK2MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219477-A1 | CYANOTRIAZOLE COMPOUNDS | Otsuka Pharmaceutical Co., Ltd. (JP) | 2023-08-02 | — | — | EP | disclosed |